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Fig. 5 | BMC Biology

Fig. 5

From: The chromosome-level genome and key genes associated with mud-dwelling behavior and adaptations of hypoxia and noxious environments in loach (Misgurnus anguillicaudatus)

Fig. 5

Expansion in fmo5 (ID: Mis0185930.1) gene involved in the detoxification function of loach Misgurnus anguillicaudatus. a The growth curves of WT and fmo5 deletion (fmo5−/−) loach. b–d Histological structure analysis of intestines from WT and fmo5−/− loach. GC, goblet cell; FMH, mucosal fold height. e,f Expressions of muc2 and some endoplasmic reticulum stress (RE stress)-related genes in intestines. g Histological structures of livers from WT and fmo5−/− loach. The black dotted boxes represent the injury area. The black and white triangles represent hepatocyte (H for short). The yellow triangles represent red blood cells (RBC for short). h,i Expressions of some RE stress-related genes in livers. muc2, Mucin; atf6, Cyclic AMP-dependent transcription factor; eif2ak3, eukaryotic translation initiation factor 2-alpha kinase 3; chop, DNA damage-inducible transcript 3 protein; Gapdh, glyceraldehyde-3-phosphate dehydrogenase. Dapi, 4',6-diamidino-2-phenylindole. * significant difference (p < 0.05); ** very significant difference (p < 0.01); *** extremely significant difference (p < 0.001)

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BMC Biology

ISSN: 1741-7007

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