Fig. 1.
From: Synaptic modifications transform neural networks to function without oxygen
Overwintered frogs maintain brain function in hypoxia. Field recordings on the lung rhythm generator region (RG, top) were measured concurrently with the respiratory motor output on the vagus root (MO, bottom), as represented in the scheme (C). Individual raw traces exemplify the control (A, n=8) and overwintered (B, n=8) responses to hypoxia. D For control frogs, activity failed after a few minutes of hypoxia, differing from overwintered frogs that presented activity for hours in the absence of oxygen (p < 0.01). The output of the network and the rhythm generator region were not different within treatments (p > 0.05, Mantel-Cox test)