Fig. 2
From: Human Satellite 1A analysis provides evidence of pericentromeric transcription
HSat1A FISH mapping (red) in human chromosomes (blue). A HSat1A mapped in GM12878. Obtained hybridization signals in acrocentric chromosomes are highlighted above. Hybridization signals are also present in chromosomes 1 and 3. Chromosomes were identified by reverse-DAPI. B HSat1A mapped in chromosomes from H1299, sequentially hybridized with human painting probes for acrocentric chromosomes. Corresponding chromosomes are visible in the table above (two different clones). The illustrative metaphase corresponds to clone I (first two rows). The column “der” for clone I shows three derivative chromosomes (non-acrocentric) with visible HSat1A signals. White arrows indicate chromosomal alterations occurring with acrocentric chromosomes and modifying the HSat1A hybridization pattern. Scale bars represent 10 μm