Table 1 Study population
From: Targeting the gut-lung axis by synbiotic feeding to infants in a randomized controlled trial
| Â | Visit 1* (1Â month of age) | Visit 2* (4Â months of age) | Visit 3* (6Â months of age) | Visit 4* (12Â months of age) | ||||
|---|---|---|---|---|---|---|---|---|
Prebiotics | Synbiotics | Prebiotics | Synbiotics | Prebiotics | Synbiotics | Prebiotics | Synbiotics | |
N (a) | 56 | 50 | 47 | 42 | 38 | 33 | 31 | 33 |
Girls, % | 43 | 56 | 45 | 50 | 47 | 52 | 52 | 52 |
Siblings | 34 | 35 | na | na | na | na | na | na |
Gestational age, weeks | 39 ± 1.07 | 40 ± 1.2 | na | na | na | na | na | na |
Age, months | 0.7 ± 0.2 | 0.8 ± 0.2 | 3.9 ± 0.3 | 4.0 ± 0.3 | 5.9 ± 0.4 | 6.0 ± 0.2 | 12.1 ± 0.4 | 12.1 ± 0.3 |
Length, cm | 55 ± 2.6 | 55.6 ± 2.5 | 65.2 ± 2.6 | 66.4 ± 3.2 | 69.9 ± 3.2 | 70.5 ± 3.7 | 81.2 ± 3.9 | 79.7 ± 5.1 |
Weight, kg | 4.0 ± 0.5 | 4.1 ± 0.5 | 6.9 ± 0.9 | 7.1 ± 0.8 | 8.1 ± 0.8 | 8.3 ± 0.8 | 10.2 ± 1.1 | 10.1 ± 0.8 |
Head circumference, cm | 36.5 ± 1.9 | 36.7 ± 1.9 | 41.5 ± 1.4 | 41.5 ± 1.3 | 43.3 ± 1.3 | 43.2 ± 1.1 | 46.2 ± 2.0 | 46.1 ± 1.3 |
BMI z-score |  − 0.7 ± 0.9 |  − 0.6 ± 0.9 |  − 0.4 ± 1.0 |  − 0.6 ± 1.2 |  − 0.5 ± 1.1 |  − 0.4 ± 1.4 |  − 1.0 ± 1.5 |  − 0.6 ± 1.5 |
LRTI | na | na | 3 | 1 | 3 | 0 | 2 | 2 |
Antibiotic use | na | na | 4 | 1 | 3 | 2 | 3 | 2 |