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Table 2 Candidate sex determination genes with gonozooid- and sex-specific expression at an expression threshold of 5 FPKM

From: XY sex determination in a cnidarian

 

Expression (FKPM)

Analysis

 

Gastro

Female gono

Male gono

NRRa

SATCb

Female coverage deficitc

Commentd

HyS2624.1

2.43

211.27

1.89

-

x

 

Unknown function

HyS0007.282

0.87

31.75

1.14

x

  

Unknown function

HyS0069.11

2.60

26.69

1.83

-

x

 

Unknown function

HyS0918.1

4.10

15.36

4.17

-

x

 

Kinase-BAR domain-SH3-coiled coil domain-containing protein

HyS0148.2

3.15

10.27

2.70

-

x

 

Unknown function

HyS4472.1

1.91

5.44

0.04

-

x

 

Gamma-glutamyltranspeptidase

HyS0067.50

1.91

5.21

0.58

x

x

 

FGF-receptor/Basigin-like protein

HyS0067.52

2.85

5.66

1.03

x

x

 

FGF-receptor/Basigin-like protein

HyS0007.322

3.09

8.03

4.23

x

-

 

Importin-11 like

HyS0007.412

2.83

0.40

943.95

x

-

 

Unknown function

HyS0057.61

2.08

0.00

859.64

x

-

 

E3 ubiquitin-protein ligase MARCHF2/3-like

HyS0057.48

2.84

0.04

531.51

x

-

 

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel

HyS0057.36

4.26

0.27

475.83

x

-

 

Unknown function

HyS0070.65

1.93

0.05

376.95

-

x

 

DBF4 zinc finger-like protein

HyS0007.262

2.50

3.75

194.30

x

-

 

Testis-Expressed Protein 45-like

HyS0057.16

3.91

3.05

32.44

x

-

 

Protein FAM221B-like

HyS0070.25

3.27

1.73

31.05

-

x

 

Unknown function

HyS0113.24

4.63

0.06

12.41

x

x

 

Pancreatic trypsin inhibitor Kunitz domain-containing protein

HyS0057.114

2.15

0.21

11.43

x

-

 

Zinc-finger domain-containing protein

HyS0007.257

1.64

0.98

11.43

x

-

 

Glycosyl transferase, family 31

HyS0120.42

2.88

0.35

9.24

x

x

 

SET domain-containing protein

HyS0007.368

3.36

0.24

8.58

x

-

 

Thrombospondin repeat domain-containing protein

HyS0067.49

0.80

2.18

10.50

x

x

 

Ankyrin repeat and LEM domain-containing protein

HyS0070.83

3.02

0.23

8.50

-

x

 

Protein patched/dispatched family member

HyS0067.65

1.39

0.27

7.65

x

x

 

Alpha-2 macroglobulin-like

HyS0007.261

1.67

0.20

7.50

x

-

 

Cytochrome P450, E-class, group I

HyS0057.88

2.81

0.19

6.35

x

-

x

Ubiquitin domain-containing protein

HyS0070.60

4.87

2.62

7.85

-

x

 

Phosphatidylinositide phosphatase SAC2

HyS0244.4

3.75

1.98

6.79

-

x

 

Elongation factor-like GTPase 1

HyS1699.2

4.16

2.40

5.84

x

x

 

Fanconi-associated nuclease 1-like

HyS0007.387

2.71

3.01

5.09

x

-

 

DNA topoisomerase 3-like

HyS0070.70

4.29

3.84

5.76

-

x

 

F-box and LRR domain containing protein

  1. aIs in the non-recombining region of linkage group 4
  2. bFlagged as sex-linked by SATC
  3. cGene with a deficit in coverage in females vs males
  4. dAuthors’ comment on potential homology or function of gene product