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Fig. 4 | BMC Biology

Fig. 4

From: The retinal pigment epithelium displays electrical excitability and lateral signal spreading

Fig. 4

Effect of TTX on INa and spikes. A I–V relations from an experiment involving inhibition of INa with 10 μM TTX. B Traces of current-clamp recordings in control conditions with spikes visible and after application of TTX from the same cell as in A; data were obtained as described in Fig. 3B; stimuli not shown. C Isolated spikes from B. D Summary of TTX experiments. Amplitudes of the largest INa and spikes were measured in three cells before and after application of TTX; values in the presence of TTX were divided by control ones and averaged (Additional file 2: Table S1)

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