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Fig. 6 | BMC Biology

Fig. 6

From: The retinal pigment epithelium displays electrical excitability and lateral signal spreading

Fig. 6

Spikes, INa and membrane time constant. A Correlation between the maximal spike and INa amplitudes; INa was measured from a recording immediately preceding the current-clamp. B, C Distribution of maximal INa amplitudes (B) and Cm values (C); the distributions are not Gaussian (P < 0.001, Shapiro-Wilk normality test). D Correlation between the maximal spike amplitudes and INa densities; INa density was obtained by dividing peak INa with the corresponding Cm value. E Plots of spike time to peaks and half-widths against membrane time constants; the spikes were obtained from voltage responses reaching the level of ca. 0 mV (−0.9 ± 2.7 mV, n = 60) from voltages below −100 mV (−131 ± 21 mV, n = 60); the correlations were characterized by P values of < 10−6

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