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Table 3 List GO terms for biological processes overrepresented in genes positively selected (Ka/Ks > 1) in large-bodied baleen whales. GO terms were collected from the human ortholog of genes with elevated non-synonymous substitution rates in large-bodied whales. GO terms from the human genome (GRCh38) were used as reference. Sorted after significance values

From: The genome of the pygmy right whale illuminates the evolution of rorquals

Term ID

Description

Number in reference

Number in query

Fold enrichment

P-value*

GO:0,007,186

G-protein-coupled receptor signaling pathway

1098

10

8.1

0.0009

GO:0,007,154

Cell communication

4549

14

2.7

0.0009

GO:0,007,165

Signal transduction

4201

12

2.5

0.0060

GO:0,050,896

Response to stimulus

5812

14

2.2

0.0095

GO:0,023,052

Signaling

4569

12

2.3

0.0095

GO:0,002,376

Immune system process

573

4

6.3

0.0109

GO:0,051,716

Cellular response to stimulus

5003

12

2.1

0.0159

GO:0,006,952

Defense response

257

2

6.9

0.0489

  1. *After false discovery rate correction following Benjamini and Hochberg