Fig. 3
From: Epigenetic regulation of human-specific gene expression in the prefrontal cortex
Human-specific signature of the H3K27ac epigenome. A Numbers of species-specific H3K27ac peaks. The orange represents H3K27ac peaks with significant enrichment unique to each primate, green represents H3K27ac peaks with significant depletion unique to each primate (n = 3) (See replicate data in Additional file 1: Tables S9 and S10). B Network visualization of genes adjacent to H3K27acHP gain. C Left panel: Relevant gene ontology categories enriched with annotated genes adjacent to H3K4me3HP loss. The x-axis denotes log10-transformed BH-corrected P values. Right panel: Network visualization of genes adjacent to H3K27acHP loss. The largest sub-networks are shown for both networks. Each circle represents an individual gene. Genes with the highest connectivity (i.e., hubs) are shown as larger sizes