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Fig. 4 | BMC Biology

Fig. 4

From: Epigenetic regulation of human-specific gene expression in the prefrontal cortex

Fig. 4

Regulation of species-specific gene expression by species-specific H3K4me3 and H3K27ac peaks. A, C Summary of the species-specific expressed genes detected in the RNA-seq dataset (A) and ssRNA-seq dataset (C). The pink and purple denote upregulated and downregulated genes specific to primates, respectively. The silhouette denotes primate identity throughout the figure (red, human; blue, chimpanzee; green, macaque). Digits in areas denote the number of genes. B, D Proportion of species-specific expressed genes regulated by species-specific H3K4me3 peaks (orange) and H3K27ac peaks (light orange) in the RNA-seq (B) and ssRNA-seq (D) datasets. The y-axis displays percentile values. C, D (n = 3) (See replicate data in Additional file 1: Table S13)

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