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  1. Content type: Research article

    The navigation of magnetotactic bacteria relies on specific intracellular organelles, the magnetosomes, which are membrane-enclosed crystals of magnetite aligned into a linear chain. The magnetosome chain acts...

    Authors: Mauricio Toro-Nahuelpan, Frank D. Müller, Stefan Klumpp, Jürgen M. Plitzko, Marc Bramkamp and Dirk Schüler

    Citation: BMC Biology 2016 14:88

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  2. Content type: Research article

    The General Control Nonderepressible 2 (GCN2) kinase is a conserved member of the integrated stress response (ISR) pathway that represses protein translation and helps cells to adapt to conditions of nutrient ...

    Authors: Rafael C. Ferraz, Henrique Camara, Evandro A. De-Souza, Silas Pinto, Ana Paula F. Pinca, Richard C. Silva, Vitor N. Sato, Beatriz A. Castilho and Marcelo A. Mori

    Citation: BMC Biology 2016 14:87

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  3. Content type: Research article

    Application of apomixis, or asexual seed formation, in crop breeding would allow rapid fixation of complex traits, economizing improved crop delivery. Identification of apomixis genes is confounded by the poly...

    Authors: David S. Rabiger, Jennifer M. Taylor, Andrew Spriggs, Melanie L. Hand, Steven T. Henderson, Susan D. Johnson, Karsten Oelkers, Maria Hrmova, Keisuke Saito, Go Suzuki, Yasuhiko Mukai, Bernard J. Carroll and Anna M. G. Koltunow

    Citation: BMC Biology 2016 14:86

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  4. Content type: Comment

    Any figure in a research article will typically represent only a small portion of the total data gained by a researcher for that experiment, and it is therefore key that the figure accurately reflects what was...

    Authors: John F. Y. Brookfield

    Citation: BMC Biology 2016 14:85

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  5. Content type: Research article

    In February 2016, a new fungal disease was spotted in wheat fields across eight districts in Bangladesh. The epidemic spread to an estimated 15,000 hectares, about 16 % of the cultivated wheat area in Banglade...

    Authors: M. Tofazzal Islam, Daniel Croll, Pierre Gladieux, Darren M. Soanes, Antoine Persoons, Pallab Bhattacharjee, Md. Shaid Hossain, Dipali Rani Gupta, Md. Mahbubur Rahman, M. Golam Mahboob, Nicola Cook, Moin U. Salam, Musrat Zahan Surovy, Vanessa Bueno Sancho, João Leodato Nunes Maciel, Antonio NhaniJúnior…

    Citation: BMC Biology 2016 14:84

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  6. Content type: Research article

    Like most animals, insects rely on their olfactory systems for finding food and mates and in avoiding noxious chemicals and predators. Most insect olfactory neurons express an odorant-specific odorant receptor...

    Authors: Suhyoung Bahk and Walton D. Jones

    Citation: BMC Biology 2016 14:83

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  7. Content type: Research article

    Peptidyl-prolyl isomerases (PPIases) catalyze cis/trans isomerization of peptidyl-prolyl bonds, which is often rate-limiting for protein folding. SlyD is a two-domain enzyme containing both a PPIase FK506-bind...

    Authors: Esben M. Quistgaard, Ulrich Weininger, Yonca Ural-Blimke, Kristofer Modig, Pär Nordlund, Mikael Akke and Christian Löw

    Citation: BMC Biology 2016 14:82

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  8. Content type: Research article

    Due to the paucity of novel antibiotics, colistin has become a last resort antibiotic for treating multidrug resistant bacteria. Colistin acts by binding the lipid A component of lipopolysaccharides and subseq...

    Authors: Vlatko Stojanoski, Banumathi Sankaran, B. V. Venkataram Prasad, Laurent Poirel, Patrice Nordmann and Timothy Palzkill

    Citation: BMC Biology 2016 14:81

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  9. Content type: Research article

    As both larvae and adults, mosquitoes encounter a barrage of immune insults, ranging from microbe-rich communities in larval habitats to ingested blood-borne pathogens in adult blood meals. Given that mosquit...

    Authors: Garrett P. League and Julián F. Hillyer

    Citation: BMC Biology 2016 14:78

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  10. Content type: Research article

    Casitas B-lineage lymphoma (Cbl or c-Cbl) is a RING ubiquitin ligase that negatively regulates protein tyrosine kinase (PTK) signalling. Phosphorylation of a conserved residue (Tyr371) on the linker helix regi...

    Authors: Lori Buetow, Giancarlo Tria, Syed Feroj Ahmed, Andreas Hock, Hao Dou, Gary J. Sibbet, Dmitri I. Svergun and Danny T. Huang

    Citation: BMC Biology 2016 14:76

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  11. Content type: Research article

    High directional persistence is often assumed to enhance the efficiency of chemotactic migration. Yet, cells in vivo usually display meandering trajectories with relatively low directional persistence, and the...

    Authors: Alba Diz-Muñoz, Pawel Romanczuk, Weimiao Yu, Martin Bergert, Kenzo Ivanovitch, Guillaume Salbreux, Carl-Philipp Heisenberg and Ewa K. Paluch

    Citation: BMC Biology 2016 14:74

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  12. Content type: Research article

    The red algae (Rhodophyta) diverged from the green algae and plants (Viridiplantae) over one billion years ago within the kingdom Archaeplastida. These photosynthetic lineages provide an ideal model to study p...

    Authors: JunMo Lee, Chung Hyun Cho, Seung In Park, Ji Won Choi, Hyun Suk Song, John A. West, Debashish Bhattacharya and Hwan Su Yoon

    Citation: BMC Biology 2016 14:75

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  13. Content type: Research article

    The Cry6 family of proteins from Bacillus thuringiensis represents a group of powerful toxins with great potential for use in the control of coleopteran insects and of nematode parasites of importance to agricult...

    Authors: Alexey Dementiev, Jason Board, Anand Sitaram, Timothy Hey, Matthew S. Kelker, Xiaoping Xu, Yan Hu, Cristian Vidal-Quist, Vimbai Chikwana, Samantha Griffin, David McCaskill, Nick X. Wang, Shao-Ching Hung, Michael K. Chan, Marianne M. Lee, Jessica Hughes…

    Citation: BMC Biology 2016 14:71

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  14. Content type: Research article

    The New World screwworm, Cochliomyia hominivorax, is a devastating pest of livestock endemic to subtropical and tropical regions of the Western hemisphere. The larvae of this species feed on the tissue of living ...

    Authors: Carolina Concha, Azhahianambi Palavesam, Felix D. Guerrero, Agustin Sagel, Fang Li, Jason A. Osborne, Yillian Hernandez, Trinidad Pardo, Gladys Quintero, Mario Vasquez, Gwen P. Keller, Pamela L. Phillips, John B. Welch, W. Owen McMillan, Steven R. Skoda and Maxwell J. Scott

    Citation: BMC Biology 2016 14:72

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  15. Content type: Research article

    ATG1 belongs to the Uncoordinated-51-like kinase protein family. Members of this family are best characterized for roles in macroautophagy and neuronal development. Apoptosis-induced proliferation (AiP) is a c...

    Authors: Mingli Li, Jillian L. Lindblad, Ernesto Perez, Andreas Bergmann and Yun Fan

    Citation: BMC Biology 2016 14:70

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  16. Content type: Research article

    After viral infection and the stimulation of some pattern-recognition receptors, TANK-binding kinase I (TBK1) is activated by K63-linked polyubiquitination followed by trans-autophosphorylation. While the activat...

    Authors: Marie Pourcelot, Naima Zemirli, Leandro Silva Da Costa, Roxane Loyant, Dominique Garcin, Damien Vitour, Ivana Munitic, Aimé Vazquez and Damien Arnoult

    Citation: BMC Biology 2016 14:69

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  17. Content type: Methodology article

    Affinity purification followed by mass spectrometry (AP/MS) is a widely used approach to identify protein interactions and complexes. In multicellular organisms, the accurate identification of protein complexe...

    Authors: Selma Waaijers, Javier Muñoz, Christian Berends, João J. Ramalho, Soenita S. Goerdayal, Teck Y. Low, Adja D. Zoumaro-Djayoon, Michael Hoffmann, Thijs Koorman, Roderick P. Tas, Martin Harterink, Stefanie Seelk, Jana Kerver, Casper C. Hoogenraad, Olaf Bossinger, Baris Tursun…

    Citation: BMC Biology 2016 14:66

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  18. Content type: Research article

    The biguanides are a family of drugs with diverse clinical applications. Metformin, a widely used anti-hyperglycemic biguanide, suppresses mitochondrial respiration by inhibiting respiratory complex I. Phenfor...

    Authors: Hannah R. Bridges, Ville A. Sirviö, Ahmed-Noor A. Agip and Judy Hirst

    Citation: BMC Biology 2016 14:65

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