From: 2R and remodeling of vertebrate signal transduction engine
Triad expression | Tetrapoda and younger | Chordata | 2ROs | Evolutionary interpretation |
---|---|---|---|---|
b: b &b | 0 | 6 | 56 | Ancestral expression conservation (b) |
b: nb & b | 5 | 11 | 123 | Subfunctionalisation through loss of PBE in one duplicate |
b: nb & nb | 7 | 12 | 133 | Gain or loss independent of gene duplication |
Conservation/sub | 0/5 = 0 | 6/11 = 0.55 | 56/123 = 0.46 | Relative rate of subfunctionalisation |
nb: b & b | 1 | 3 | 18 | Gain or loss independent of gene duplication |
nb: nb & b | 7 | 11 | 58 | Neofunctionalisation through gain of PBE in one duplicate |
nb: nb & nb | 12 | 9 | 78 | Ancestral expression conservation (nb) |
Conservation/neo | 12/7 = 1.71 | 9/11 = 0.82 | 78/58 = 1.34 | Relative rate of neofunctionalisation |
Sub/neo ratio | 5/7 = 0.71 | 11/11 = 1 | 123/58 = 2.12 | Ratio of sub- to neofunctionalisation |