Articles

Sort by
Previous Page Page 1 of 46 Next Page
  1. Research article

    Ion- and water-binding sites inside an occluded hourglass pore of a trimeric intracellular cation (TRIC) channel

    Trimeric intracellular cation (TRIC) channels are crucial for Ca2+ handling in eukaryotes and are involved in K+ uptake in prokaryotes. Recent studies on the representative members of eukaryotic and prokaryotic T...

    Xiaomin Ou, Jianli Guo, Longfei Wang, Hanting Yang, Xiuying Liu, Jianyuan Sun and Zhenfeng Liu

    BMC Biology 2017 15:31

    Published on: 22 April 2017

  2. Research article

    Single swim sessions in C. elegans induce key features of mammalian exercise

    Exercise exerts remarkably powerful effects on metabolism and health, with anti-disease and anti-aging outcomes. Pharmacological manipulation of exercise benefit circuits might improve the health of the sedent...

    Ricardo Laranjeiro, Girish Harinath, Daniel Burke, Bart P. Braeckman and Monica Driscoll

    BMC Biology 2017 15:30

    Published on: 10 April 2017

  3. Research article

    OsLG3 contributing to rice grain length and yield was mined by Ho-LAMap

    Most agronomic traits in rice are complex and polygenic. The identification of quantitative trait loci (QTL) for grain length is an important objective of rice genetic research and breeding programs.

    Jianping Yu, Haiyan Xiong, Xiaoyang Zhu, Hongliang Zhang, Huihui Li, Jinli Miao, Wensheng Wang, Zuoshun Tang, Zhanying Zhang, Guoxin Yao, Qiang Zhang, Yinghua Pan, Xin Wang, M. A. R. Rashid, Jinjie Li, Yongming Gao…

    BMC Biology 2017 15:28

    Published on: 6 April 2017

  4. Methodology article

    A multi-animal tracker for studying complex behaviors

    Animals exhibit astonishingly complex behaviors. Studying the subtle features of these behaviors requires quantitative, high-throughput, and accurate systems that can cope with the often rich perplexing data.

    Eyal Itskovits, Amir Levine, Ehud Cohen and Alon Zaslaver

    BMC Biology 2017 15:29

    Published on: 6 April 2017

  5. Research article

    Giardia intestinalis mitosomes undergo synchronized fission but not fusion and are constitutively associated with the endoplasmic reticulum

    Mitochondria of opisthokonts undergo permanent fission and fusion throughout the cell cycle. Here, we investigated the dynamics of the mitosomes, the simplest forms of mitochondria, in the anaerobic protist pa...

    Luboš Voleman, Vladimíra Najdrová, Ásgeir Ástvaldsson, Pavla Tůmová, Elin Einarsson, Zdeněk Švindrych, Guy M. Hagen, Jan Tachezy, Staffan G. Svärd and Pavel Doležal

    BMC Biology 2017 15:27

    Published on: 3 April 2017

  6. Research article

    TriPer, an optical probe tuned to the endoplasmic reticulum tracks changes in luminal H2O2

    The fate of hydrogen peroxide (H2O2) in the endoplasmic reticulum (ER) has been inferred indirectly from the activity of ER-localized thiol oxidases and peroxiredoxins, in vitro, and the consequences of their gen...

    Eduardo Pinho Melo, Carlos Lopes, Peter Gollwitzer, Stephan Lortz, Sigurd Lenzen, Ilir Mehmeti, Clemens F. Kaminski, David Ron and Edward Avezov

    BMC Biology 2017 15:24

    Published on: 27 March 2017

  7. Research article

    Transcriptome analysis of pancreatic cells across distant species highlights novel important regulator genes

    Defining the transcriptome and the genetic pathways of pancreatic cells is of great interest for elucidating the molecular attributes of pancreas disorders such as diabetes and cancer. As the function of the d...

    Estefania Tarifeño-Saldivia, Arnaud Lavergne, Alice Bernard, Keerthana Padamata, David Bergemann, Marianne L. Voz, Isabelle Manfroid and Bernard Peers

    BMC Biology 2017 15:21

    Published on: 21 March 2017

  8. Methodology article

    Low-cell-number, single-tube amplification (STA) of total RNA revealed transcriptome changes from pluripotency to endothelium

    In addition to messenger RNA (mRNA), noncoding RNAs (ncRNAs) are essential components in cellular machineries for translation and splicing. Besides their housekeeping functions, ncRNAs are involved in cell typ...

    Yi-Hsuan Lee, Ya-Wen Hsueh, Yao-Hung Peng, Kung-Chao Chang, Kuen-Jer Tsai, H. Sunny Sun, Ih-Jen Su and Po-Min Chiang

    BMC Biology 2017 15:22

    Published on: 21 March 2017

  9. Research article

    Albugo-imposed changes to tryptophan-derived antimicrobial metabolite biosynthesis may contribute to suppression of non-host resistance to Phytophthora infestans in Arabidopsis thaliana

    Plants are exposed to diverse pathogens and pests, yet most plants are resistant to most plant pathogens. Non-host resistance describes the ability of all members of a plant species to successfully prevent col...

    David C. Prince, Ghanasyam Rallapalli, Deyang Xu, Henk-jan Schoonbeek, Volkan Çevik, Shuta Asai, Eric Kemen, Neftaly Cruz-Mireles, Ariane Kemen, Khaoula Belhaj, Sebastian Schornack, Sophien Kamoun, Eric B. Holub, Barbara A. Halkier and Jonathan D. G. Jones

    BMC Biology 2017 15:20

    Published on: 20 March 2017

  10. Commentary

    The important challenge of quantifying tropical diversity

    The tropics are the repository of much of the world’s biodiversity, yet are undersampled relative to temperate regions. To help fill this knowledge gap, a paper in BMC Biology explores diversity patterns in tropi...

    Anne E. Magurran

    BMC Biology 2017 15:14

    Published on: 7 March 2017

  11. Research article

    Exploring the floristic diversity of tropical Africa

    Understanding the patterns of biodiversity distribution and what influences them is a fundamental pre-requisite for effective conservation and sustainable utilisation of biodiversity. Such knowledge is increas...

    Marc S. M. Sosef, Gilles Dauby, Anne Blach-Overgaard, Xander van der Burgt, Luís Catarino, Theo Damen, Vincent Deblauwe, Steven Dessein, John Dransfield, Vincent Droissart, Maria Cristina Duarte, Henry Engledow, Geoffrey Fadeur, Rui Figueira, Roy E. Gereau, Olivier J. Hardy…

    BMC Biology 2017 15:15

    Published on: 7 March 2017

  12. Research article

    Structural basis for potency differences between GDF8 and GDF11

    Growth/differentiation factor 8 (GDF8) and GDF11 are two highly similar members of the transforming growth factor β (TGFβ) family. While GDF8 has been recognized as a negative regulator of muscle growth and di...

    Ryan G. Walker, Magdalena Czepnik, Erich J. Goebel, Jason C. McCoy, Ana Vujic, Miook Cho, Juhyun Oh, Senem Aykul, Kelly L. Walton, Gauthier Schang, Daniel J. Bernard, Andrew P. Hinck, Craig A. Harrison, Erik Martinez-Hackert, Amy J. Wagers, Richard T. Lee…

    BMC Biology 2017 15:19

    Published on: 3 March 2017

  13. Review

    Meta-evaluation of meta-analysis: ten appraisal questions for biologists

    Meta-analysis is a statistical procedure for analyzing the combined data from different studies, and can be a major source of concise up-to-date information. The overall conclusions of a meta-analysis, however...

    Shinichi Nakagawa, Daniel W. A. Noble, Alistair M. Senior and Malgorzata Lagisz

    BMC Biology 2017 15:18

    Published on: 3 March 2017

  14. Research article

    Population genomics reveals that an anthropophilic population of Aedes aegypti mosquitoes in West Africa recently gave rise to American and Asian populations of this major disease vector

    The mosquito Aedes aegypti is the main vector of dengue, Zika, chikungunya and yellow fever viruses. This major disease vector is thought to have arisen when the African subspecies Ae. aegypti formosus evolved fr...

    Jacob E. Crawford, Joel M. Alves, William J. Palmer, Jonathan P. Day, Massamba Sylla, Ranjan Ramasamy, Sinnathamby N. Surendran, William C. Black, Arnab Pain and Francis M. Jiggins

    BMC Biology 2017 15:16

    Published on: 28 February 2017

  15. Software

    Rapid, precise quantification of bacterial cellular dimensions across a genomic-scale knockout library

    The determination and regulation of cell morphology are critical components of cell-cycle control, fitness, and development in both single-cell and multicellular organisms. Understanding how environmental fact...

    Tristan Ursell, Timothy K. Lee, Daisuke Shiomi, Handuo Shi, Carolina Tropini, Russell D. Monds, Alexandre Colavin, Gabriel Billings, Ilina Bhaya-Grossman, Michael Broxton, Bevan Emma Huang, Hironori Niki and Kerwyn Casey Huang

    BMC Biology 2017 15:17

    Published on: 21 February 2017

  16. Research article

    Long-term microfluidic tracking of coccoid cyanobacterial cells reveals robust control of division timing

    Cyanobacteria are important agents in global carbon and nitrogen cycling and hold great promise for biotechnological applications. Model organisms such as Synechocystis sp. and Synechococcus sp. have advanced our...

    Feiqiao Brian Yu, Lisa Willis, Rosanna Man Wah Chau, Alessandro Zambon, Mark Horowitz, Devaki Bhaya, Kerwyn Casey Huang and Stephen R. Quake

    BMC Biology 2017 15:11

    Published on: 14 February 2017

  17. Research article

    How flies are flirting on the fly

    Flies have some of the most elaborate visual systems in the Insecta, often featuring large, sexually dimorphic eyes with specialized “bright zones” that may have a functional role during mate-seeking behavior....

    Courtney Eichorn, Michael Hrabar, Emma C. Van Ryn, Bekka S. Brodie, Adam J. Blake and Gerhard Gries

    BMC Biology 2017 15:2

    Published on: 14 February 2017

  18. Research article

    Enhancing circadian clock function in cancer cells inhibits tumor growth

    Circadian clocks control cell cycle factors, and circadian disruption promotes cancer. To address whether enhancing circadian rhythmicity in tumor cells affects cell cycle progression and reduces proliferation...

    Silke Kiessling, Lou Beaulieu-Laroche, Ian D. Blum, Dominic Landgraf, David K. Welsh, Kai-Florian Storch, Nathalie Labrecque and Nicolas Cermakian

    BMC Biology 2017 15:13

    Published on: 14 February 2017

  19. Research article

    MicroRNA miR-29 controls a compensatory response to limit neuronal iron accumulation during adult life and aging

    A widespread modulation of gene expression occurs in the aging brain, but little is known as to the upstream drivers of these changes. MicroRNAs emerged as fine regulators of gene expression in many biological...

    Roberto Ripa, Luca Dolfi, Marco Terrigno, Luca Pandolfini, Aurora Savino, Valeria Arcucci, Marco Groth, Eva Terzibasi Tozzini, Mario Baumgart and Alessandro Cellerino

    BMC Biology 2017 15:9

    Published on: 13 February 2017

Previous Page Page 1 of 46 Next Page