From: A high-throughput chemically induced inflammation assay in zebrafish
Compound | Mode of action | Concentration (μM) | Significant effect | Reference |
---|---|---|---|---|
Ibuprofen | COX inhibitor | 1 | *** | [38] |
10 | *** | |||
50 | * | |||
Diclofenac | COX inhibitor | 1.5 | *** | |
3 | *** | |||
SP600125 | JNK inhibitor | 20 | * | [40] |
50 | ** | |||
100 | ** | |||
200 | *** | |||
Trans-resveratrol | COX-1 inhibitor | 1 | - | [41] |
10 | ** | |||
100 | *** | |||
Mifepristone (RU486) | Progesterone and GR antagonist | 1 | - | [42] |
10 | ** | |||
100 | *** | |||
Dexamethasone | Steroidal nitric oxide synthase inhibitor | 10 | - | [43] |
100 | ** | |||
1,000 | *** | |||
Indomethacin | COX inhibitor | 1 | ** | [39] |
10 | *** | |||
100 | *** | |||
Rosiglitazone | PPAR-γ agonist | 0.5 | * | [44] |
1 | ** | |||
10 | * | |||
Aspirin | COX inhibitor | 10 | - | [39] |
20 | ** | |||
Hydrocortisone | Steroidal GR agonist | 1 | - | [45] |
10 | - | |||
100 | - | |||
300 | * | |||
Sulindac | NS COX-1 inhibitor | 1 | ** | [46] |
10 | *** | |||
50 | *** | |||
100 | *** |