Figure 2
ATP requirements in cell maintenance and division. Using a model based on differential equations for growth rates [10], the fraction of ATP, fATP, consumed for biosynthetic (red dashed line) versus maintenance (black dashed line) purposes in cells is plotted as a function of doubling time in days. Typical doubling times for unicellular organisms such as Escherichia coli and Saccharomyces cerevisiae are shown, as well as for typical cancer cell lines (HeLa) and solid tumors.