Fig. 3

Telomere shortening does not affect energy expenditure or food intake in G2-Terc^−/− mice. a Daily food intake of 12 month old male and female G2-Terc^−/− and control mice (male n = 8 WT, n = 9 KO; female n = 7 WT, n = 8 KO). b-d Metabolic cage measurements of 12-month-old male and female G2-Terc^−/− and control mice (male n = 9 WT, n = 11 KO; female n = 9 WT, n = 8 KO) Grey areas indicate dark cycle and white areas the light cycle. b Correlation of energy expenditure to body weight. c Cumulative locomotor activity. d Respiratory exchange ratio (RER) and mean total, dark and light cycle RER. All data are shown as mean ± SE. For a statistical analysis was performed using an unpaired t-test. Statistical analysis for the energy expenditure against body weight was analyzed by ANCOVA. A two-way ANOVA with Sidak’s multiple comparison test was used for c and multiple t-tests for d. Red and black dots represent male mice. Green and purple dots represent female mice