Fig. 7
From: Enhanced tyrosine sulfation is associated with chronic kidney disease-related atherosclerosis
Correlations between enhanced tyrosine sulfation and CKD-related atherosclerosis. Chronic kidney disease (CKD) is associated with increased levels of inorganic sulfate (SO4−2) and the consequently enhanced tyrosine sulfation, which leads to the increased sulfation of specific adhesion molecules and chemokine receptors, including CCR2 and CCR5. This contributes to monocytes/macrophages activation, finally favoring the process of CKD-related atherosclerosis