Fig. 1
From: A new compact adenine base editor generated through deletion of HNH and REC2 domain of SpCas9
Screening single deletion for ABE. a Schematic of domain deletions of ABE8.17. b Schematic showing the mCherry/EGFP reporter. c Representative fluorescence microscopy images of deletion variants analysis. d Comparison of editing efficiency of ABE8.17 deletion variants by flow cytometry analysis (FCA). e Comparison of editing efficiency of ABE8.17 deletion variants in HEK293T cell line by plasmid transient transfection (n = 3)