Fig. 3

Patient crisis modelling. Simulated acyl-CoA accumulation in the mitochondrial compartment at 150 µM cytosolic palmitoyl-CoA compared to measured acylcarnitines in the urine of MCADD patients during hypoketotic hypoglycaemia (n = 3). The blue bars (measured data, y-axis on the right) represent the median and the range of the data (minimum and maximum)