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Fig. 5 | BMC Biology

Fig. 5

From: Personalised modelling of clinical heterogeneity between medium-chain acyl-CoA dehydrogenase patients

Fig. 5

Metabolic control analysis. Flux and mitochondrial CoASH concentration control coefficients (blue and yellow, respectively) in a control (A) and an MCADD (B) model. Enzymes are displayed in descending order according to absolute flux control. Flux was defined as the sum of all NADH-producing reactions. Simulations were carried out at 150 µM cytosolic palmitoyl-CoA

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