Personalised modelling of clinical heterogeneity between medium-chain acyl-CoA dehydrogenase patients

Table 2 K_m values for CoASH of CoASH-requiring mitochondrial enzymes

Enzyme	Pathway	K_m (mM)	Reference
CrAT	Carnitine shuttle	0.038–0.0888	[86, 91]
MCKAT	mFAO	0.0022–0.0384	[108, 185]
αKDH	TCA cycle	0.0025	[186]
PDH	TCA cycle / glycolysis	0.013–0.025	[186, 187]

ISSN: 1741-7007