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Fig. 7 | BMC Biology

Fig. 7

From: Identification of cell subpopulations associated with disease phenotypes from scRNA-seq data using PACSI

Fig. 7

Application of PACSI on spatial transcriptomic data. A The spatial transcriptomic data was embedded in UMAP space (left) and unbiased clustering of spatial transcriptomics spots (right). B Histopathological annotations of human breast cancer sample in which malignant cells are highlighted in red circles (top). H&E images for spatial transcriptomic data overlaid with the locations of the spatial transcriptomics spots colored according to their annotation (bottom). The red dots are PACSI-identified spots associated with poor survival and the gray dots represent the rest of the spots in the spatial transcriptomic data. C Visualization of RAP1GAP, TFAP2A, and KRT23 expression in spots under the tissue

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BMC Biology

ISSN: 1741-7007

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