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Table 4 Gene Ontology enrichment results for CpG loci identified as significant in placenta specific analysis

From: Sexually dimorphic methylation patterns characterize the placenta and blood from extremely preterm newborns

 

Ontology

Term

N

DE

P.DE

FDR

GO:0030216

BP

Keratinocyte differentiation

136

8

6.26E − 10

1.43E − 05

GO:0031424

BP

Keratinization

55

6

1.46E − 09

1.66E − 05

GO:0009913

BP

Epidermal cell differentiation

198

8

1.41E − 08

0.0001

GO:0008544

BP

Epidermis development

320

9

3.34E − 08

0.0002

GO:0043588

BP

Skin development

260

8

1.40E − 07

0.0006

GO:0001533

CC

Cornified envelope

44

4

2.23E − 06

0.0085

  1. BP biological process, CC cellular component, N number of genes in the GO or KEGG term, DE number of genes that are differentially methylated, P.DE p value for over-representation of the GO or KEGG term