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Table 1 SPT16 depletion alters mRNA transcription and abundance, with most prominent effects after 12 + h of depletion

From: FACT regulates pluripotency through proximal and distal regulation of gene expression in murine embryonic stem cells

Hours depleted

0

3

6

12

12 + 24-h washout

24

24 [RNA-seq]

mRNAs up

3

58

214

1366

1815

5398

3977

mRNAs down

53

5

174

1932

1427

5000

3781

  1. Control samples and SPT16-depleted samples were separately pooled between cell lines for downstream analyses. Only transcripts with an adjusted p-value of < 0.05 are displayed (analyzed with DESeq2)
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BMC Biology

ISSN: 1741-7007

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