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Fig. 1 | BMC Biology

Fig. 1

From: Diminished activation of excitatory neurons in the prelimbic cortex leads to impaired working memory capacity in mice

Fig. 1

WMC was significantly reduced in 3-month-old 5XFAD mice compared to littermate WT mice. a-c Performance correct rate, correct option rate and correct rejection rate of mice during the NMSS-rule learning phase (Two-way ANOVA, all p > 0.05). d WMC of mice during the NMMS-rule learning phase (Two-way ANOVA, p > 0.05). e WMC of mice during the test phase (Unpaired Student’s t test, ***p < 0.001). f Percent correct at each capacity level (Two-way ANOVA, ****p < 0.0001). g Percentage of mice succeeded at each capacity level (Two-way ANOVA, ****p < 0.0001). h Average errors at each capacity level (Two-way ANOVA, ****p < 0.0001). WT: n = 22; TG: n = 20. Data are presented as the mean ± SEM

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