Fig. 2

The activation of PrL neurons was associated with WMC. a,b Representative images show the FOS⁺ neurons in the PrL and IL of each group of mice. c Representative image show the PrL and IL. d The number of FOS⁺ neurons in the PrL (Two-way ANOVA, interaction: p > 0.05, task: p < 0.0001, genotype: p < 0.05; post hoc Tukey’s tests, *p < 0.05, ****p < 0.0001). n = 12 slices from four mice per group. e Relationship between the number of FOS⁺ neurons in the PrL and WMC in the task group mice (Linear regression, *p < 0.05). n = 8. f The number of FOS⁺ neurons in the IL (Two-way ANOVA, all p > 0.05; post hoc Tukey’s tests, all p > 0.05). n = 12 slices from four mice per group. g Relationship between the number of FOS⁺ neurons in the IL and WMC of in the task group mice (Linear regression, p > 0.05). n = 8. Data are presented as the mean ± SEM