Fig. 5
From: Regulatory changes associated with the head to trunk developmental transition
TF activity dynamics during the head to trunk transition. A Scatter plot of TF activity dynamics between E7.5 and E8.5. The y-axis represents the differences in TF binding activity. Each point represents a TF, points colored in red have significantly different activity scores (p-value < 0.05). Labelled points have a differential |Activity Score|> 0.2. (B-H) Average ATAC-seq profiles of Pou5f1 (B), Sox2 (C), Nanog (D), Cdx1 (E), Cdx2 (F), Hoxc9 (G) and Tbxt (H) binding sites. Red profiles correspond to E7.5, blue profiles to E8.5, n indicates the number of binding sites used to calculate the average profiles