Fig. 1

Deletion of Faap100 causes germ cell loss after birth in both sexes. A Gross morphology of ovaries and ovary/body weight ratio of 3-month-old wild-type and Faap100^−/− mice. n = 5 per genotype. Scale bars, 500 μm. B Haematoxylin & eosin (H&E) and DDX4-stained sections of ovaries at the indicated ages. Scale bars, 100 μm. C Gross morphology of testes and testis/body weight ratio of 3-month-old wild-type and Faap100^−/− mice. n = 5 per genotype. Scale bars, 2 mm. D H&E- and DDX4-stained sections of testes at the indicated ages. Scale bars, 100 μm. Data are shown as the mean ± SD (A, C). Unpaired two-tailed Student’s t-test (A) and two-tailed Mann–Whitney U-test (C), **P < 0.01 and ***P < 0.001