Fig. 3

4-parameter analysis in detecting minor motor deficits in comparison of Sham and TBI mice. A Study timeline with the Rotarod test in the TBI and Sham group: BL testing is performed 3 days prior to the operation and others at dpo3, dpo14, dpo21. B-E Raw averaged data from Trial 2 to Trial 4 at different time points: First latency to fall (s), Longest duration on rod (s), Maximal distance on rod (cm) and Number of falls. F-H Normalized data with normalization to the average of Trial 2 to Trial 4 in baseline testing individually: First latency to fall (%), Longest duration (%) and Maximal distance on rod (%). I) Normalized data with normalization by subtracting to the average of Trial 2 to Trial 4 in baseline testing individually: delta number of falls. Statistical analysis was carried out by the Kruskal-Wallis test followed by Dunn’s correction. n = 8 in Sham group with circular symbols and n = 24 in TBI group with triangle symbols, asterisks indicate significances: *p < 0.05, **p < 0.01, ***p < 0.001