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Fig. 4 | BMC Biology

Fig. 4

From: Beyond rational—biosensor-guided isolation of 100 independently evolved bacterial strain variants and comparative analysis of their genomes

Fig. 4

Growth and l-histidine production of C. glutamicum CgHis2 variants with different genomic modifications. C. glutamicum CgHis2 ΔfasB Δpyk served as starting variant for the construction of various strains combining three or four genomic modifications, which exhibited significant increase in l-histidine production (yellow). Δpyk always refers to the pyk1 gene. C. glutamicum CgHis2 ΔfasB Δcps served as starting variant for the construction of various strains with no improvement of product formation (Additional file 1: Fig. S9). Data represent average values and standard deviation of three independent technical replicates

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