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Fig. 3 | BMC Biology

Fig. 3

From: Single-nucleus transcriptome inventory of giant panda reveals cellular basis for fitness optimization under low metabolism

Fig. 3

Cell profiles of ventricles and metabolic differences among vCMs. A UMAP visualization of ventricles and left and right counterparts. B Cell fraction of seven vCM clusters in left and right ventricles and GO enrichment analysis examining shared and distinct functions for each vCM cluster. C Function differences between clusters 2 and 3 and clusters 0, 1, 4, 8, and 9, with hierarchical clustering dendrogram of gene expression above them. D Monocle 2 pseudotime-ordered trajectory of vCMs. E Expression difference of FoxO TFs and their feedback loop involving in cardiac muscle remodeling between two vCM subtypes. F Transcriptomic comparison of genes responsible for lipoprotein uptake and oxidation in two vCM subtypes. G Violin plots showed a significant expressional difference of essential genes for the FA metabolic process. H Expression of genes encoding acyl-CoA synthetase. I Examination of genes for re-esterification of fatty acyl CoA and export

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BMC Biology

ISSN: 1741-7007

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