Cuticular competing endogenous RNAs regulate insecticide penetration and resistance in a major agricultural pest

Table 1 Toxicity of malathion against the MR and MS strains of B. dorsalis

Strains	LD₅₀ (95% ng/fly)	Y = LD – P line	χ²	Resistance ratio (RR)	Topical/injected ratio
Topical application
MS	64.37 (56.18–73.40)	Y = 3.04X – 6.41	3.63	-	-
MR	3452.50 (3081.60–3890.15)	Y = 3.11X – 11.95	1.07	53.64^a	-
Injection
MS	44.11 (38.15–58.97)	Y = 5.92X – 9.74	6.77	0.69^b	1.46^d
MR	1,333.77 (1281.53–1383.49)	Y = 8.57X – 26.78	3.03	30.24^c	2.59^e

LD₅₀, dosage resulting in the death of 50% of the test animals. Topical application means that malathion was applied to the pronotum using a PB600-1 repeating dispenser. Injection means that the malathion was injected into the body of the fly through the thorax
^aLD₅₀ of MR topical application/MS topical application
^bLD₅₀ of MS injection/MS topical application
^cLD₅₀ of MR injection/MS injection
^dLD₅₀ of MS topical application/MS injection
^eLD₅₀ of MR topical application/MR injection

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