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Fig. 5 | BMC Biology

Fig. 5

From: Prefoldin 2 contributes to mitochondrial morphology and function

Fig. 5

Loss of PFD2 leads to decreased abundance of mitochondrial proteins at permissive growth temperature. A–C, E, F Volcano plots showing all identified proteins that localize to mitochondria (light pink circles in A), mitochondrial ribosome (dark pink circle in B), cytosolic ribosome (green circle in C), chaperones and protein folding (yellow circle in E), and proteasome (brown circle in F). D Interaction network of all proteins significantly downregulated. In yellow are proteins identified as chaperones and in pink are proteins localized to mitochondria including mitochondrial ribosomes and in green are proteins of the cytosolic ribosome marked. G Interaction network of all proteins significantly upregulated. In pink are proteins with mitochondrial localization, in yellow are proteins identified as chaperones and in brown are proteins of the proteasome system marked. WT, wild type

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