Fig. 1
From: Expression and splicing mediate distinct biological signals
pairedGSEA and confounder-mediated false discoveries. A Flowchart of the pairedGSEA R package and its functions (red and blue rounded squares). The gray and white backgrounds in the boxes indicate data and functionality, respectively. B The distribution of false positives, i.e., the number of significantly differentially expressed genes only found when not corrected for confounders, across the 199 comparisons. C Histogram of the false discovery rate when not correcting for confounders. Significance is defined as having an FDR-adjusted p-value of < 0.05