Fig. 3

C57 females show distinct patterns of space use and social associations. A C57 females explore more of the available resource zone spaces than C57 males and WD males and females, as shown by three representative females from each genotype (rows, indicated by three letter individual identification codes). Each 2 × 4 grid shows the eight resource zones on each of the 10 days (columns) of a trial, with warmer colors indicating a high frequency of RFID reads in a given zone. B All sex and genotype combinations visit similar numbers of zones (unique per day) on the first several days of the trial, but C57 females increase the numbers of zones visited relative to any other sex or genotype combination as the trial continues. C C57 females visit more cumulative resource zones over the course of the trial period compared to all other sex and genotype combinations. D WD females show a strong and sustained preference for their cage mates, whereas C57 female preferences for cage mates quickly fall to null expectation levels (as indicated by the dashed line). Note that mice were placed in resource zones with their cage mates on the first day of the trial. Data are plotted as means ± SEM