Fig. 4

A workflow for reconstructing the ancestral genome based on present-day populations. I. Local ancestry inference of modern human genome. The segments inferred as HM in 5 of the 10 results were treated as candidate segments. Grey dots denote variants. II. Assembly of HM ancestral genomes using candidate segments. Each time, a segment was randomly selected from the optional starting sites and extended back no more than 6 kb. The low-coverage regions of the ancestral segments were skipped. The pentagrams denote the starting sites for candidates.