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Fig. 1 | BMC Biology

Fig. 1

From: DNA methylation haplotype block signatures responding to Staphylococcus aureus subclinical mastitis and association with production and health traits

Fig. 1

DNA methylation landscape at important genomic functional regions indicating their possible association with gene expression. A The distribution of DNA methylation at regions in relation to CpG island (CGI). L: left, R: right. B The DNA methylation level at genetic regions illustrating the classic valley-like change of DNA methylation level (CpG sites) around transcription start sites (TSS). C–E The scatterplot and fitting curves of DNA methylation level of regulatory regions, including promoters (C), first exons (D), and first introns (E), and expression level of genes. The higher the expression level of genes, the lower methylation level of their regulatory regions. F The methylation level trends around genes grouped by ranked gene expression level. Up‑region and down-region represent the upstream and downstream region of genes, respectively. G An enlarged view of figure F near TSS, showing the steeper methylation level trend around TSS for genes with higher expression levels

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BMC Biology

ISSN: 1741-7007

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