Fig. 7
From: Differentiation is accompanied by a progressive loss in transcriptional memory
Manhattan distances comparison between generation 1 sisters and non related T2EC cells using subsets of genes. (A) Boxplots of the Manhattan distances computed between all cells from the same biological conditions using all the 55 memory genes. (B) Boxplots of the Manhattan distances computed between all cells from the same biological conditions using the 55 most variable genes. (C) Venn diagram of the 55 memory genes and the 55 most variable genes, 16 genes are common between both categories. (D) Boxplots of the Manhattan distances computed between all cells from the same biological conditions using the most variable genes, excluding the memory genes. (E) Density plot of the distribution of adjusted p-values from Wilcoxon test for mean Manhattan distance comparisons between conditions using 55 randomly draw genes, 1000 times. Blue curve is the p-values distribution of mean distance comparison between self-renewing sister-cells vs self-renewing non related cells. Yellow curve is the p-values distribution of mean distance comparison between differentiating sister-cells vs differentiating non related cells. P-value at 5% is presented as dotted grey vertical line