Fig. 6

The genomics alteration underlying TRLS. A The waterfall plot depicted the differences in frequently mutated genes (FMGs) of lung adenocarcinoma between the two groups. B Top 20 FMGs at somatic mutations between the high- and low-risk groups. C, D Correlations analysis of TRLS with mRNAsi (C) and TMB (D). E–G Distribution of tumor neoantigen number (E); FGA, FGG, and FGL (F); and copy number load (G) in the high- and low-risk groups. P values are shown as *P < 0.05, **P < 0.01, and ***P < 0.001