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Fig. 2 | BMC Biology

Fig. 2

From: Insights for disease modeling from single-cell transcriptomics of iPSC-derived Ngn2-induced neurons and astrocytes across differentiation time and co-culture

Fig. 2

A MetaNeighbor analysis of our bulk and pseudobulk expression data with in vivo data from two in vivo studies. Ex_Cor, excitatory cortical; HEW, human embryo week; Astro, astrocytes; Oligo, oligodendrocytes; OPC, oligodendrocyte precursor cells; Endo, endothelial. B, C Seurat integration analysis of our hiPSC-N cells with neuronal cells from two in vivo datasets. B our cells colored by condition. C our cells colored by Louvain cluster. Ex_Cor, excitatory cortical; HEW, human embryo week. D, E Seurat integration analysis of our hiPSC-A cells with non-neuronal cell from two in vivo datasets. D Our cells colored by condition. E Our cells colored by Louvain cluster. SMC, smooth muscle cells; VEC, vascular endothelial cells; VLMC, vascular leptomeningeal cells. Astro, astrocytes; Oligo, oligodendrocytes

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BMC Biology

ISSN: 1741-7007

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