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Fig. 3 | BMC Biology

Fig. 3

From: Insights for disease modeling from single-cell transcriptomics of iPSC-derived Ngn2-induced neurons and astrocytes across differentiation time and co-culture

Fig. 3

Integration analysis of our Ngn2-induced neuronal data with other single-cell data in Ngn2-induced neurons. A UMAP of Seurat-integrated data from our study and two other scRNA-seq studies of Ngn2-induced neurons (Schornig et al. and Lin et al.), colored by cell cluster. B Same UMAP colored by weeks of Ngn2 induction. C Proportion of cells from different time points in each cell cluster. D Cells from individual studies visualized in the same UMAP as in A and B, again colored by weeks of Ngn2-induction. E Expression of marker genes used to delineate diversity in the lineage composition of Ngn2-indced neurons. F MetaNeighbor analysis of in vitro cells and in vivo cell types (both divided by time points and by study: W, weeks of Ngn2 induction or gestational week; HE, human embryo, individual cell lines used are also indicated)

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