From: Prediction of blood–brain barrier penetrating peptides based on data augmentation with Augur
Property | Group 1 | Group 2 | Group 3 |
---|---|---|---|
Charge | Neutral | Negatively charged | Positively charged |
A, C, F, G, H, I, L, M, N, P, Q, S, T, V, W, Y | D, E | K, R | |
Hydrophobicity | Hydrophobicity | Neutral | Polar |
C, F, I, L, M, V, W | A, G, H, P, S, T, Y | D, E, K, N, Q, R | |
Normalized van der Waals volume | 0–2.78 | 2.95–4.0 | 4.03–8.08 |
A, C, D, G, P, S, T | E, I, L, N, Q, V | F, H, K, M, R, W, Y | |
Polarity | 4.9–6.2 | 8.0–9.2 | 10.4–13.0 |
C, F, I, L, M, V, W, Y | A, G, P, S, T | D, E, H, K, N, Q, R | |
Polarizability | 0–0.108 | 0.128–0.186 | 0.219–0.409 |
A, D, G, S, T | C, E, I, L, N, P, Q, V | F, H, K, M, R, W, Y | |
Secondary structure | Coil | Helix | Strand |
D, G, N, P, S | A, E, H, K, L, M, Q, R | C, F, I, T, V, W, Y | |
Solvent accessibility | Buried | Intermediate | Exposed |
A, C, F, G, I, L, V, W | H, M, P, S, T, Y | D, E, K, N, R, Q |