Fig. 2
From: Fast and accurate variant identification tool for sequencing-based studies
When tested against in silico variants in the human gut microbiome WGS samples, QuickVariants shows higher accuracy than bcftools by identifying (a) almost no false positive indels (0–2 FP indels, median = 0), (b) twofold to 16-fold fewer false negative indels (FN indels) (median), (c) 2.0-fold fewer median FP point mutations, and (d) 1.3-fold fewer median FN point mutations. a,d In point plots, error bars signify a 95% confidence interval, and the central points denote the mean values. Samples were labeled by the number of in silico point mutations inserted into the corrected assembly (n = 27, 9 WGS datasets and 3 aligners)