Fig. 6

Short-term hypoxia modulates inflammatory signaling in seal cells. A Overlap between genes DE at all early time points (15 min, 30 min, 60 min) versus control for seal and human cells. Heatmap shows log₁₀(fold change) for 42 DE genes shared between species. B Reactome pathway enrichment for genes DE at all early time points. C, D Functional interaction networks and select enriched pathways for seal (C) and human (D) genes DE at all early time points