Methylation with age. a. CSX tags sampled from anagen follicles. Individual hair values ("X") were scattered but averages ("O") from individuals exhibited no increase after two years of age. Tag diversity (number of unique tags found in the 8 sampled follicle tags) also exhibited an increase before two years of age. Graphs on the right give an expanded view of values early in life. The earliest hairs are from fetuses of 22 and 32 weeks estimated gestational ages, and a term stillborn. Symbols and trend lines are green up to two years of age, and red after infancy. b. Average SOX10 methylation also exhibited relatively constant values after two years of age.