BMC Biology

Fifteen Years of BMC Biology

To mark our fifteen-year anniversary, in this special collection we bring together pieces from a selection of the authors, reviewers, and editorial board members who have been part of our journey, sharing their stories and perspectives

When a Physicist Wanders into Biology…

In his interview, KC Huang discusses the excitement of pursuing insights at scales from molecules to cellular communities, how new tools open research perspectives, how to create an empowering lab environment, and why integrating chemistry with physics and biology can bring us closer to asking the right questions

Open Questions: Why are Babies Rarely Born with Cancer?

In her Open Questions Michele Monje asks why cancer occurs only very rarely during the prenatal and early postnatal period, despite this being a period of enormous growth and most intense development

Evolving Eukaryotes

In his interview, Joel Dacks discusses how researching the evolution of organelles helps understanding the mechanisms of trafficking in cells, why new experimental model systems, going beyond plants, animals and fungi, are needed to accelerate research into cell biology, and the importance of a constructive peer review process

Host-Parasite Interactions

In her interview, Emily Troemel describes studying host-parasite interactions in C. elegans to bring new understanding of the mechanisms shaping immune responses, why she thinks we’ll soon discover a new form of immunity, and discusses the role of peer review in training future scientists

Unravelling Rainforest Diversity

In his interview, Thomas Couvreur discusses the challenges and opportunities in biodiversity research, how digitization of plant specimens from herbaria and museums worldwide accelerates our understanding of biosystems, and the importance of knowing how to code

Articles

Content type: Research article
| 15 November 2018

Classifying human promoters by occupancy patterns identifies recurring sequence elements, combinatorial binding, and spatial interactions

Authors: Xinyi Yang and Martin Vingron
Content type: Research article
| 5 November 2018

Common ancestry of heterodimerizing TALE homeobox transcription factors across Metazoa and Archaeplastida

Authors: Sunjoo Joo, Ming Hsiu Wang, Gary Lui, Jenny Lee, Andrew Barnas, Eunsoo Kim, Sebastian Sudek, Alexandra Z. Worden and Jae-Hyeok Lee
Content type: Interview
| 1 November 2018

From bacterial genomics to clinical epidemiology: an interview with Bill Hanage

Authors: William P. Hanage
Content type: Interview
| 1 November 2018

Host-parasite interactions: an interview with Emily Troemel

Authors: Emily Troemel
Content type: Interview
| 1 November 2018

Evolutionary development and morphological modifications of the brain: an interview with Angelika Stollewerk

Authors: Angelika Stollewerk

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Research
Loss of males from mixed-sex societies in termites
Toshihisa Yashiro, Nathan Lo, Kazuya Kobayashi, Tomonari Nozaki, Taro Fuchikawa, Nobuaki Mizumoto, Yusuke Namba and Kenji Matsuura
Published on: 8 October 2018

Research
Identification of cell types in a mouse brain single-cell atlas using low sampling coverage
Aparna Bhaduri, Tomasz J Nowakowski, Alex A Pollen and Arnold R Kriegstein
Published on: 11 October 2018

Research
Ontogenetic and phylogenetic simplification during white stripe evolution in clownfishes
Pauline Salis, Natacha Roux, Olivier Soulat, David Lecchini, Vincent Laudet and Bruno Frédérich
Published on: 05 September 2018

Research
Quantifying and reducing spurious alignments for the analysis of ultra-short ancient DNA sequences
Cesare de Filippo, Matthias Meyer and Kay Prüfer
Published on: 25 October 2018

Research
Food perception without ingestion leads to metabolic changes and irreversible developmental arrest in C. elegans
Rebecca E. W. Kaplan, Amy K. Webster, Rojin Chitrakar, Joseph A. Dent and L. Ryan Baugh
Published on: 27 September 2018

Interview
From plant immunity to food security: an interview with Ksenia Krasileva
Ksenia Krasileva
Published on: 1 November 2018

Open Questions
Open questions: CRISPR biology
Eugene V. Koonin
Published on: 24 September 2018

Review
Tissue macrophages: heterogeneity and functions
Siamon Gordon and Annette Plüddemann
Published on: 29 June 2017

Interview
Studying the microbiome and its complexities: an interview with Alan Walker
Alan Walker
Published on: 1 November 2018

Open Questions
Open questions: knowing who’s who in multicellular animals is not always as simple as we imagine
Robin A. Weiss
Published on: 15 October 2018

Content type: Research article
| 24 September 2009

scribblemutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs

Authors: Gregory R Leong, Karen R Goulding, Nancy Amin, Helena E Richardson and Anthony M Brumby
Content type: Review
| 28 October 2011

Molecular dynamics simulations and drug discovery

Authors: Jacob D Durrant and J Andrew McCammon
Content type: Question and Answer
| 30 September 2011

Q&A: What is the Golgi apparatus, and why are we asking?

Authors: Sean Munro
Content type: Research article
| 23 November 2009

Mapping cortical hubs in tinnitus

Authors: Winfried Schlee, Nadia Mueller, Thomas Hartmann, Julian Keil, Isabel Lorenz and Nathan Weisz
Content type: Research article
| 12 November 2014

Reagent and laboratory contamination can critically impact sequence-based microbiome analyses

Authors: Susannah J Salter, Michael J Cox, Elena M Turek, Szymon T Calus, William O Cookson, Miriam F Moffatt, Paul Turner, Julian Parkhill, Nicholas J Loman and Alan W Walker

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Focus: Neurobiology in Health and Disease

Read the latest Reviews on neurobiology across BMC flagship journals.

Ultrasound and dynamic functional imaging in vascular cognitive impairment and Alzheimer’s disease
Branko Malojcic, Panteleimon Giannakopoulos, Farzaneh A. Sorond, Elsa Azevedo, Marina Diomedi, Janja Pretnar Oblak, Nicola Carraro, Marina Boban, Laszlo Olah, Stephan J. Schreiber, Aleksandra Pavlovic, Zsolt Garami, Nantan M. Bornstein and Bernhard Rosengarten
Published in BMC Medicine on: 09 February 2017

The biological function of the cellular prion protein: an update
Marie-Angela Wulf, Assunta Senatore and Adriano Aguzzi
Published in BMC Biology on: 02 May 2017

New insights into the generation and role of de novo mutations in health and disease
Rocio Acuna-Hidalgo, Joris A. Veltman and Alexander Hoischen
Published in Genome Biology on: 28 November 2016

Recurrent de novo mutations in neurodevelopmental disorders: properties and clinical implications
Amy B. Wilfert, Arvis Sulovari, Tychele N. Turner, Bradley P. Coe and Evan E. Eichler
Published in Genome Medicine on: 27 November 2017