BMC Biology

Flying foxes travel far and wide

Justin Welbergen and colleagues track Australia-wide movements of three flying-fox species, showing that these large bats are extremely mobile, travelling thousands of kilometers and leading nomadic lives.

Sensitizing tumors to therapy via the microbiome

Anne Kiltie and colleagues examine the impact of high-fibre diets on radiation in tumour xenografts, finding that diet-induced sensitivity to radiation was associated with a modified microbiome and increased B. acidifaciens abundance.

Toward efficient cell-specific delivery of proteins

Andreas Plückthun and colleagues re-engineered the pore-forming translocation unit of a bacterial protein toxin to create a stable construct capable of cell-specific delivery of high loads of proteins to the cytosol.

Large-scale discovery of male reproductive genes

Thomas Garcia, Christian Coarfa and colleagues integrated human and mouse RNA-seq datasets to identify male reproductive tract-specific genes, and functionally tested new epididymis- and testis-specific targets via mouse knockouts, demonstrating their requirement for male fertility.

Cytosolic surveillance of mitochondrial precursor proteins

Jan Riemer and colleagues describe the stabilizing property of the oxidoreductase MIA40’s C-terminal region, as a factor controlling cytosolic surveillance of mitochondrial intermembrane space proteins’ import.

Call for papers: Research Synthesis and Meta-research in Biology

We’re inviting submissions to our new Series guest edited by Shinichi Nakagawa, Julia Koricheva, Malcolm Macleod and Wolfgang Viechtbauer.

Articles

Genetic modifiers ameliorate endocytic and neuromuscular defects in a model of spinal muscular atrophy

Authors: Melissa B. Walsh, Eva Janzen, Emily Wingrove, Seyyedmohsen Hosseinibarkooie, Natalia Rodriguez Muela, Lance Davidow, Maria Dimitriadi, Erika M. Norabuena, Lee L. Rubin, Brunhilde Wirth and Anne C. Hart

Content type: Research article

16 September 2020
A non-photosynthetic green alga illuminates the reductive evolution of plastid electron transport systems

Authors: Motoki Kayama, Jun-Feng Chen, Takashi Nakada, Yoshiki Nishimura, Toshiharu Shikanai, Tomonori Azuma, Hideaki Miyashita, Shinichi Takaichi, Yuichiro Kashiyama and Ryoma Kamikawa

Content type: Research article

16 September 2020
Altered brain-wide auditory networks in a zebrafish model of fragile X syndrome

Authors: Lena Constantin, Rebecca E. Poulsen, Leandro A. Scholz, Itia A. Favre-Bulle, Michael A. Taylor, Biao Sun, Geoffrey J. Goodhill, Gilles C. Vanwalleghem and Ethan K. Scott

Content type: Research article

16 September 2020
Independent glial subtypes delay development and extend healthy lifespan upon reduced insulin-PI3K signalling

Authors: Nathaniel S. Woodling, Arjunan Rajasingam, Lucy J. Minkley, Alberto Rizzo and Linda Partridge

Content type: Research article

14 September 2020
A molecular insight into the dissociable regulation of associative learning and motivation by the synaptic protein neuroligin-1

Authors: Jiaqi Luo, Jessica M. Tan and Jess Nithianantharajah

Content type: Research article

14 September 2020

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Research
Genomic history of the Italian population recapitulates key evolutionary dynamics of both Continental and Southern Europeans
Marco Sazzini et al.
Published on: 22 May 2020

Research
Wonky whales: the evolution of cranial asymmetry in cetaceans
Ellen Coombs et al.
Published on: 10 July 2020

Research
Tandem gene duplications drive divergent evolution of caffeine and crocin biosynthetic pathways in plants
Zhichao Xu et al.
Published on: 18 June 2020

Research
Relationship between oxygen consumption and neuronal activity in a defined neural circuit
Suzan Özugur et al.
Published on: 03 July 2020

Review
X-ray computed tomography in life sciences
Shelley D. Rawson et al.
Published 27 February 2020

Comment
The merger that made us
Buzz Baum and David Baum
Published 24 June 2020

Review
Protein assembly systems in natural and synthetic biology
Giulio Chiesa et al.
Published: 26 March 2020

Comment
Improving the usability and comprehensiveness of microbial databases
Caitlin Loeffler et al.
Published: 07 April 2020

scribblemutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs

Authors: Gregory R Leong, Karen R Goulding, Nancy Amin, Helena E Richardson and Anthony M Brumby

Content type: Research article

24 September 2009
Molecular dynamics simulations and drug discovery

Authors: Jacob D Durrant and J Andrew McCammon

Content type: Review

28 October 2011
Q&A: What is the Golgi apparatus, and why are we asking?

Authors: Sean Munro

Content type: Question and Answer

30 September 2011
Mapping cortical hubs in tinnitus

Authors: Winfried Schlee, Nadia Mueller, Thomas Hartmann, Julian Keil, Isabel Lorenz and Nathan Weisz

Content type: Research article

23 November 2009
The first metazoa living in permanently anoxic conditions

Authors: Roberto Danovaro, Antonio Dell'Anno, Antonio Pusceddu, Cristina Gambi, Iben Heiner and Reinhardt Møbjerg Kristensen

Content type: Research article

6 April 2010