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Revisiting the zebrafish ‘hypothalamus”

Using genetic lineage-tracing, Kei Yamamoto and colleagues track the development of the inferior lobe in zebrafish, showing that this structure is not homologous to the mammalian lateral hypothalamus, and postulating that it might be involved in multimodal sensory integration.

Evolving social cooperation in microbial communities

Yiwen Chu and colleagues show that behavioral heterogeneity in quorum sensing can stabilize social cooperative behaviors in bacteria, explaining the coexistence of cooperation and defection during evolution of microbial populations.

Supporting oocyte survival

Chao Wang and colleagues examine the factors regulating the life span of fetal oocytes, showing that GSK-3β signaling supports oocyte survival through regulation of Tap63 and DNA damage checkpoint signaling.

Probing complex life history traits

Basten Snoek, Hinrich Schulenburg and Jan Kammenga  derive multi-parent recombinant inbred C. elegans lines and use them to identify new QTLs for life history traits such as lifespan, stress resistance and pathogen responses.

Call for Papers - "Engineering Biology"

We are delighted to invite submission of Research papers to our latest series, under the Guest Editorship of James Collins, Sophien Kamoun, Nicola Patron, James Wells, and Pamela Silver. For more details, please read here!

Call for Papers - "Microbiome Biology"

BMC Biology and Genome Biology are inviting submission for our upcoming joint special issue on Microbiome Biology scheduled for publication in Spring 2019


The golden death bacillus Chryseobacterium nematophagum is a novel matrix digesting pathogen of nematodes
Antony P. Page, Mark Roberts, Marie-Anne Félix, Derek Pickard, Andrew Page and William Weir
Published on: 28 February 2019

Identification of functional long non-coding RNAs in C. elegans
Alper Akay, David Jordan, Isabela Cunha Navarro, Tomasz Wrzesinski, Chris P. Ponting, Eric A. Miska and Wilfried Haerty
Published on: 18 February 2019

Ontogenetic and phylogenetic simplification during white stripe evolution in clownfishes
Pauline Salis, Natacha Roux, Olivier Soulat, David Lecchini, Vincent Laudet and Bruno Frédérich
Published on: 5 September 2018

Analysis of sea star larval regeneration reveals conserved processes of whole-body regeneration across the metazoa
Gregory A. Cary, Andrew Wolff, Olga Zueva, Joseph Pattinato and Veronica F. Hinman
Published on: 22 February 2019

The landscape of sex-differential transcriptome and its consequent selection in human adults
Moran Gershoni and Shmuel Pietrokovski
Published on: 7 February 2017

Open questions: how to get developmental biology into shape?
Timothy E. Saunders and Philip W. Ingham
Published on: 22 February 2019

Tissue macrophages: heterogeneity and functions
Siamon Gordon and Annette Plüddemann
Published on: 29 June 2017 

Circadian oscillator proteins across the kingdoms of life: structural aspects
Reena Saini, Mariusz Jaskolski and Seth J. Davis
Published on: 18 February 2019

Open questions: CRISPR biology
Eugene V. Koonin
Published on: 24 September 2018

Detecting positive selection in the genome
Tom R. Booker, Benjamin C. Jackson and Peter D. Keightley
Published on: 30 October 2017

  1. Content type: Research article


    Authors: Winfried Schlee, Nadia Mueller, Thomas Hartmann, Julian Keil, Isabel Lorenz and Nathan Weisz

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Focus: Cancer

Read the latest reviews covering advances in cancer biology and treatment across BMC flagship journals.

Second-line treatment for advanced NSCLC without actionable mutations: is immunotherapy the ‘panacea’ for all patients?
Alessandro Morabito
Published in BMC Medicine on: 16 February 2018

Nothing in cancer makes sense except…
Mel Greaves
Published in BMC Biology on: 21 February 2018

Strategies for monitoring and combating resistance to combination kinase inhibitors for cancer therapy
Leanne G. Ahronian and Ryan B. Corcoran
Published in Genome Medicine on: 21 April 2017

Timing somatic events in the evolution of cancer
Clemency Jolly and Peter Van Loo
Published in Genome Biology on: 24 July 2018

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