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The human microbiome in evolution

From the "In the Light of Evolution" series - Davenport, Sanders, Knight and colleagues review how evolutionary insights may help delineate the assembly and effects of the microbiome on human health: from comparison with our ancestors, to microbial medicine

Host-microbe symbioses: friends (but sometimes foes) within

From our “In the Light of Evolution” series, Nicole Gerardo and Gregory Hurst discuss the complex evolutionary ecology of hosts and microbes, and open questions in how microbes affect host phenotype and evolution

Energy landscapes of protein folding

Part of our "Proten Quality Control at Membranes" series - this review covers how outer membrane proteins overcome their crowded, hydrophobic environment  

Memory retrieval in drug addiction

Zheng and colleagues report a role for miR-105 in coupling memory and addiction, through inducing expression of dopamine D1 receptors at glutamatergic terminals

Collections’ Highlights

Part of our “Plant Signals” series – a Q&A from Sebastien Paque and Dolf Weijers on Auxin, and how it influences almost anything 

Video Abstract: David Kingsley and Colleagues

A change to the ratio of splice products of MSX2A drove dorsal spine evolution in threespine sticklebacks

Featured Review

Quantitative imaging of mammalian transcriptional dynamics: from single cells to whole embryos​​​​​​​

Ziqing W. Zhao, Melanie D. White, Stephanie Bissiere, Valeria Levi and Nicolas Plachta

Published on: 23 December 2016

Articles

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Methodology
Investigating the physiology of viable but non-culturable bacteria by microfluidics and time-lapse microscopy
Rosemary A. Bamford, Ashley Smith, Jeremy Metz, Georgina Glover, Richard W. Titball and Stefano Pagliara 
Published on: 21 December 2017

Methodology
Cell fixation and preservation for droplet-based single-cell transcriptomics
Jonathan Alles, Nikos Karaiskos†, Samantha D. Praktiknjo†, Stefanie Grosswendt, Philipp Wahle, Pierre-Louis Ruffault, Salah Ayoub, Luisa Schreyer, Anastasiya Boltengagen, Carmen Birchmeier, Robert Zinzen, Christine Kocks and Nikolaus Rajewsky
Published on: 19 May 2017

Research
The landscape of sex-differential transcriptome and its consequent selection in human adults
Moran Gershoni and Shmuel Pietrokovski
Published on: 7 February 2017

Research 
A multi-trait systems approach reveals a response cascade to bleaching in corals
Stephanie G. Gardner, Jean-Baptiste Raina, Matthew R. Nitschke, Daniel A. Nielsen, Michael Stat, Cherie A. Motti, Peter J. Ralph and Katherina Petrou
Published on: 7 December 2017

Research 
Dorsal spine evolution in threespine sticklebacks via a splicing change in MSX2A​​​​​​​
Timothy R. Howes,Brian R. Summers† and David M. Kingsley
Published on: 7 December 2017

Review
The human microbiome in evolution
Emily R. Davenport, Jon G. Sanders, Se Jin Song, Katherine R. Amato, Andrew G. Clark and Rob Knight​​​​​​​
Published on: 27 December 2017

Opinion
On causal roles and selected effects: our genome is mostly junk
W. Ford Doolittle and Tyler D. P. Brunet
Published on: 5 December 2017

Question and Answer
Q&A: Friends (but sometimes foes) within: the complex evolutionary ecology of symbioses between host and microbes
Nicole Gerardo and Gregory Hurst​​​​​​​
Published on: 27 December 2017

Review
Outer membrane protein folding from an energy landscape perspective​​​​​​​
Bob Schiffrin, David J. Brockwell and Sheena E. Radford​​​​​​​
Published on: 21 December 2017

Forum
Non-model model organisms
James J. Russell, Julie A. Theriot, Pranidhi Sood, Wallace F. Marshall, Laura F. Landweber, Lillian Fritz-Laylin, Jessica K. Polka, et al.
Published on: 29 June 2017

  1. Content type: Research article

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    Authors: Winfried Schlee, Nadia Mueller, Thomas Hartmann, Julian Keil, Isabel Lorenz and Nathan Weisz

  2. Content type: Forum

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    Authors: Wallace F Marshall, Kevin D Young, Matthew Swaffer, Elizabeth Wood, Paul Nurse, Akatsuki Kimura, Joseph Frankel, John Wallingford, Virginia Walbot, Xian Qu and Adrienne HK Roeder

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Aims and scope

BMC Biology is a broad scope journal covering all areas of biology. Our content includes research articles, new methods and tools. BMC Biology also publishes reviews, Q&A, and commentaries.

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