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Katrina Morris and colleagues present the genome of the quail and characterize a number of its features, showcasing quail as a model of choice for studying infectious and immune responses, as well as social behaviors.
Daniel Croll and colleagues present a reference-quality pangenome of the wheat fungal pathogen Zymoseptoria tritici, characterizing the conservation of genomic sequences, variation at loci relevant for pathogenicity, and the contribution of transposone content across 19 worldwide isolates.
Raman Akinyanju Lawal and Oliver Hanotte unravel the origin of genetic diversity in the domestic chicken via a whole-genome analysis of village chickens from geographically distinct regions and the wild junglefowl ancestral species.
Liam Keegan and Mary O’Connell demonstrate that altering flows of membranes and proteins through Tor-regulated autophagy compensates for synaptic deficits occurring upon suppression of RNA editing in the brain.
Irene Adrian-Kalchhauser and colleagues present the genome of the invasive round goby, and identify genomic features that may make it a successful colonizer.
Natalie Elia and colleagues present a powerful, easy-to-implement tool for live-cell labeling of proteins with small, genetic code expansion-based fluorescent probes.
Vânia C. S. Pankievicz, Thomas B. Irving, Lucas G. S. Maia & Jean-Michel Ané
Published on: 03 December 2019
Research
Evolutionary superscaffolding and chromosome anchoring to improve Anopheles genome assemblies
Robert M. Waterhouse et al.
Published on: 02 January 2020
Research
Charting the diversity of uncultured viruses of Archaea and Bacteria
F. H. Coutinho et al.
Published on: 29 December 2019
Research
Long live the king: chromosome-level assembly of the lion (Panthera leo) using linked-read, Hi-C, and long-read data
Ellie E. Armstrong et al.
Published on: 08 January 2020
Research
The X chromosome of the German cockroach, Blattella germanica, is homologous to a fly X chromosome despite 400 million years divergence
Richard P. Meisel et al.
Published on: 05 December 2019
Methodology
Spatiotemporal mapping of RNA editing in the developing mouse brain using in situ sequencing reveals regional and cell-type-specific regulation
Elin Lundin et al.
Published on: 14 January 2020
Review
Unlocking the origins and biology of domestic animals using ancient DNA and paleogenomics
Gillian P. McHugo et al.
Published 02 December 2019
Review
Are we there yet? The long walk towards the development of efficient symbiotic associations between nitrogen-fixing bacteria and non-leguminous crops
Vânia C. S. Pankievicz et al.
Published 03 December 2019
Review
The microbiome of the upper respiratory tract in health and disease
Christina Kumpitsch, Kaisa Koskinen, Veronika Schöpf & Christine Moissl-Eichinger
Published: 07 November 2019
Review
The human gut bacteria Christensenellaceae are widespread, heritable, and associated with health
Jillian L. Waters & Ruth E. Ley
Published: 28 October 2019
Review
Studying the gut virome in the metagenomic era: challenges and perspectives
Sanzhima Garmaeva, Trishla Sinha, Alexander Kurilshikov, Jingyuan Fu, Cisca Wijmenga & Alexandra Zhernakova
Published: 28 October 2019
Read the latest papers on Disease Genetics across BMC flagship journals.
Spectrum of mutations in monogenic diabetes genes identified from high-throughput DNA sequencing of 6888 individuals
Vikas Bansal et al.
Published in BMC Medicine 06 December 2017
Pathological mutations differentially affect the self-assembly and polymerisation of the innate immune system signalling adaptor molecule MyD88
Ailis O'Carroll et al.
Published in BMC Biology 24 December 2018
Complex structural variants in Mendelian disorders: identification and breakpoint resolution using short- and long-read genome sequencing
Alba Sanchis-Juan et al.
Published in Genome Medicine 07 December 2018
Chromatin interactome mapping at 139 independent breast cancer risk signals
Jonathan Beesley et al.
Published in Genome Biology 02 January 2020
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