A model based on molecular dynamics simulations portrays ESCRT-III as a multifilament assembly of beads connected by springs, capable of driving the full range of experimentally reported ESCRT-III dependent membrane remodelling.
Zhernakova and colleagues discuss the viral component of the gut ecosystem, the challenges of studying the bacteriophages that shape our gut microbiomes, and what we know so far of their role in health and disease.
Jillian Waters and Ruth Ley review what we have learned about the Christensenellaceae, a recently-discovered family of gut bacteria that is widespread, heritable, and significantly associated with human health.
Spiral cleavage patterns produce radially arranged blastomeres, but spiralian larvae later metamorphose into fully bilateral juveniles. The cell lineage of the Platynereis larval episphere may help reveal how bilateral symmetry of the head emerges.
Ramon-Mateu and colleagues use the comb jelly as a model to show that cell proliferation is required for regeneration in ctenophores, but is separable from wound healing; and might shed light on regenerative diversity among metazoans.
Authors: Isidro Álvarez-Escribano, Christoph Sasse, Jin Woo Bok, Hyunsoo Na, Mojgan Amirebrahimi, Anna Lipzen, Wendy Schackwitz, Joel Martin, Kerrie Barry, Gabriel Gutiérrez, Sara Cea-Sánchez, Ana T. Marcos, Igor V. Grigoriev, Nancy P. Keller, Gerhard H. Braus and David Cánovas