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Call for papers: “Protein Quality Control at Membranes” series

Our new thematic series is now welcoming submissions of Research articles! Visit the series’ homepage to see the current Reviews and Research, and find more information about submitting

Mapping phosphoinositides at the shoot apical meristem

Part of our "Plant Signals" series – Olivier Hamant and colleagues suggest a role for phosphoinositide patterning in stem cell maintenance, shaped by mechanical stresses

WorMachine: machine learning-based phenotypic analysis tool for worms

Oded Rechavi and colleagues present WorMachine, software to quantify visible C. elegans phenotypes in an automated, high-throughput manner

Identifying optogenetic tools for Controlling GPCR signalling

Robert Lucas and colleagues provide a cell-based assay for screening the coupling of candidate GPCRs to different G proteins

Collections’ Highlights

From our “In the Light of Evolution” series – a review from Rusty Gage and colleagues on how mobile elements might have shaped the evolving human brain.

Video Abstract: evolution of cleavage patterns

Andreas Hejnol and colleagues describe how evolutionary changes in patterns of blastomere cleavage impact the specification of cell fates

Featured Review

How driving endonuclease genes can be used to combat pests and disease vectors

H. Charles J. Godfray, Ace North and Austin Burt

Published on: 11 September 2017


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WorMachine: machine learning-based phenotypic analysis tool for worms
Adam Hakim, Yael Mor, Itai Antoine Toker, Amir Levine, Moran Neuhof, Yishai Markovitz and Oded Rechavi
Published on: 16 January 2018

De novo assembly of the complex genome of Nippostrongylus brasiliensis using MinION long reads
Adam Hakim, Yael Mor, Itai Antoine Toker, Amir Levine, Moran Neuhof, Yishai Markovitz and Oded Rechavi
Published on: 14 December 2017

Cell fixation and preservation for droplet-based single-cell transcriptomics
Jonathan Alles, Nikos Karaiskos†, Samantha D. Praktiknjo†, Stefanie Grosswendt, Philipp Wahle, Pierre-Louis Ruffault, Salah Ayoub, Luisa Schreyer, Anastasiya Boltengagen, Carmen Birchmeier, Robert Zinzen, Christine Kocks and Nikolaus Rajewsky
Published on: 19 May 2017

The landscape of sex-differential transcriptome and its consequent selection in human adults
Moran Gershoni and Shmuel Pietrokovski
Published on: 7 February 2017

Pangenome analyses of the wheat pathogen Zymoseptoria tritici reveal the structural basis of a highly plastic eukaryotic genome
Clémence Plissonneau, Fanny E. Hartmann and Daniel Croll
Published on: 11 January 2018

The human microbiome in evolution
Emily R. Davenport, Jon G. Sanders, Se Jin Song, Katherine R. Amato, Andrew G. Clark and Rob Knight
Published on: 27 December 2017

Will human influences on evolutionary dynamics in the wild pervade the Anthropocene?​​​​​​​
Fanie Pelletier and David W. Coltman​​​​​​​
Published on: 15 January 2018

Hsp70 at the membrane: driving protein translocation​​​​​​​
Elizabeth A. Craig
Published on: 17 January 2018

Question and Answer
Q&A: Expansion microscopy
Ruixuan Gao, Shoh M. Asano and Edward S. Boyden
Published on: 19 June 2017

On causal roles and selected effects: our genome is mostly junk
W. Ford Doolittle and Tyler D. P. Brunet
Published on: 5 December 2017

  1. Content type: Research article


    Authors: Winfried Schlee, Nadia Mueller, Thomas Hartmann, Julian Keil, Isabel Lorenz and Nathan Weisz

  2. Content type: Forum


    Authors: Wallace F Marshall, Kevin D Young, Matthew Swaffer, Elizabeth Wood, Paul Nurse, Akatsuki Kimura, Joseph Frankel, John Wallingford, Virginia Walbot, Xian Qu and Adrienne HK Roeder

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Aims and scope

BMC Biology is a broad scope journal covering all areas of biology. Our content includes research articles, new methods and tools. BMC Biology also publishes reviews, Q&A, and commentaries.