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Targeting protein quality control pathways in breast cancer

Cancer cells thrive in stress conditions that cause protein damage. Sannino and Brodsky review the mechanisms, and how we might exploit these processes in treating breast cancer

Hybrid de novo genome assembly – the gray mouse lemur

Incorporating datasets from different genomic technologies can result in improved genome assemblies – here illustrated by the gray mouse lemur genome

Forum - Membrane dynamics and organelle biogenesis

Ten perspectives on the lipid transport mechanisms necessary to drive membrane expansion during organelle biogenesis and cell growth

Methodology – screening for inhibitors of protein-protein interactions

In vivo assays to screen for small-molecule inhibitors of PPIs are limited. Wong et al present a new method, characterised by a novel Mdm2-binding site in p53

Collections’ Highlights

From “In the Light of Evolution”– a Review from Waglechner and Wright on antibiotic resistance: it’s bad, but why isn’t it worse?

Research: Gershoni and Pietrokovski

“The landscape of sex-differential transcriptome and its consequent selection in human adults”

Featured Review 

Digital tissue and what it may reveal about the brain

Josh L. Morgan and Jeff W. Lichtman

Published on: 30 October 2017


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  1. Content type: Research article


    Authors: Winfried Schlee, Nadia Mueller, Thomas Hartmann, Julian Keil, Isabel Lorenz and Nathan Weisz

  2. Content type: Forum


    Authors: Wallace F Marshall, Kevin D Young, Matthew Swaffer, Elizabeth Wood, Paul Nurse, Akatsuki Kimura, Joseph Frankel, John Wallingford, Virginia Walbot, Xian Qu and Adrienne HK Roeder

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Aims and scope

BMC Biology is the flagship biology journal of the BMC series, pioneer of open access publishing. Our scope includes research and methodology articles, review, Q&A and comment, across all of biology and with a publication policy that combines selection for special interest and importance with a commitment to serving authors well.

Latest collections

Thematic series
Protein Quality Control at Membranes
BMC Biology

Thematic series
New Tools for Neurobiology
BMC Biology

Cross journal collection
In the Light of Evolution

Thematic series
What is Wrong With This Picture?
BMC Biology

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