BMC Biology

How Gardenias became chemists

The genome sequence of Gardenia jasminoides yields insights into the ways gene duplications drove the divergent evolution of the crocin and caffeine biosynthetic pathways.

Dissecting the functions of acetyl-CoA in Toxoplasma Gondii

Using multi-omics approaches, Dominique Soldati-Favre and colleagues examine the role of distinct acetyl-CoA subcellular pools in the pathogen Toxoplasma gondii, identifying their distinct roles in the synthesis of parasite-specific fatty acids, and impact on metabolic processes.

The rise of metabolic diversity across the Candidate Phyla Radiation

Mapping bacterial genomes and metabolic capacities allowed the identification of the evolutionary processes driving metabolic diversity in the Candidate Phyla Radiation lineages.

The merger that made us

Buzz Baum and David Baum comment on the evolution of eukaryotic cells, and how discoveries of new microbes chart the path to eukaryogenesis.

Targeted approaches for epigenetic age predictions

DNA methylation analysis based on pyrosequencing, ddPCR, and BBA-seq approaches enables high-precision epigenetic age-predictions and demonstrated that the stochastic evolution of age-associated methylation patterns enables epigenetic clocks for individual DNA strands.

Call for papers: Research Synthesis and Meta-research in Biology

We’re inviting submissions to our new Series guest edited by Shinichi Nakagawa, Julia Koricheva, Malcolm Macleod and Wolfgang Viechtbauer.

Articles

Wonky whales: the evolution of cranial asymmetry in cetaceans

Authors: Ellen J. Coombs, Julien Clavel, Travis Park, Morgan Churchill and Anjali Goswami

Content type: Research article

10 July 2020
Comparative whole genome DNA methylation profiling across cattle tissues reveals global and tissue-specific methylation patterns

Authors: Yang Zhou, Shuli Liu, Yan Hu, Lingzhao Fang, Yahui Gao, Han Xia, Steven G. Schroeder, Benjamin D. Rosen, Erin E. Connor, Cong-jun Li, Ransom L. Baldwin, John B. Cole, Curtis P. Van Tassell, Liguo Yang, Li Ma and George E. Liu

Content type: Research article

6 July 2020
The roles of hybridization and habitat fragmentation in the evolution of Brazil’s enigmatic longwing butterflies, Heliconius nattereri and H. hermathena

Authors: Darli Massardo, Nicholas W. VanKuren, Sumitha Nallu, Renato R. Ramos, Pedro G. Ribeiro, Karina L. Silva-Brandão, Marcelo M. Brandão, Marília B. Lion, André V. L. Freitas, Márcio Z. Cardoso and Marcus R. Kronforst

Content type: Research article

3 July 2020
TDP-43 prevents retrotransposon activation in the Drosophila motor system through regulation of Dicer-2 activity

Authors: Giulia Romano, Raffaella Klima and Fabian Feiguin

Content type: Research article

3 July 2020
Epigenomics and genotype-phenotype association analyses reveal conserved genetic architecture of complex traits in cattle and human

Authors: Shuli Liu, Ying Yu, Shengli Zhang, John B. Cole, Albert Tenesa, Ting Wang, Tara G. McDaneld, Li Ma, George E. Liu and Lingzhao Fang

Content type: Research article

3 July 2020

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Research
Evolutionary superscaffolding and chromosome anchoring to improve Anopheles genome assemblies
Robert M. Waterhouse et al.
Published on: 02 January 2020

Research
Charting the diversity of uncultured viruses of Archaea and Bacteria
F. H. Coutinho et al.
Published on: 29 December 2019

Research
Long live the king: chromosome-level assembly of the lion (Panthera leo) using linked-read, Hi-C, and long-read data
Ellie E. Armstrong et al.
Published on: 08 January 2020

Research
The X chromosome of the German cockroach, Blattella germanica, is homologous to a fly X chromosome despite 400 million years divergence
Richard P. Meisel et al.
Published on: 05 December 2019

Methodology
Spatiotemporal mapping of RNA editing in the developing mouse brain using in situ sequencing reveals regional and cell-type-specific regulation
Elin Lundin et al.
Published on: 14 January 2020

Review
Unlocking the origins and biology of domestic animals using ancient DNA and paleogenomics
Gillian P. McHugo et al.
Published 02 December 2019

Review
Are we there yet? The long walk towards the development of efficient symbiotic associations between nitrogen-fixing bacteria and non-leguminous crops
Vânia C. S. Pankievicz et al.
Published 03 December 2019

Review
The microbiome of the upper respiratory tract in health and disease
Christina Kumpitsch, Kaisa Koskinen, Veronika Schöpf & Christine Moissl-Eichinger
Published: 07 November 2019

Review
The human gut bacteria Christensenellaceae are widespread, heritable, and associated with health
Jillian L. Waters & Ruth E. Ley
Published: 28 October 2019

Review
Studying the gut virome in the metagenomic era: challenges and perspectives
Sanzhima Garmaeva, Trishla Sinha, Alexander Kurilshikov, Jingyuan Fu, Cisca Wijmenga & Alexandra Zhernakova
Published: 28 October 2019

scribblemutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs

Authors: Gregory R Leong, Karen R Goulding, Nancy Amin, Helena E Richardson and Anthony M Brumby

Content type: Research article

24 September 2009
Molecular dynamics simulations and drug discovery

Authors: Jacob D Durrant and J Andrew McCammon

Content type: Review

28 October 2011
Q&A: What is the Golgi apparatus, and why are we asking?

Authors: Sean Munro

Content type: Question and Answer

30 September 2011
Mapping cortical hubs in tinnitus

Authors: Winfried Schlee, Nadia Mueller, Thomas Hartmann, Julian Keil, Isabel Lorenz and Nathan Weisz

Content type: Research article

23 November 2009
Q&A: What are exosomes, exactly?

Authors: James R. Edgar

Content type: Question and Answer

13 June 2016