Skip to main content


Amyloid beta and interneuron circuit dysfunction

Jeehyun Kwag and colleagues dissect the contributions of parvalbumin and somatostatin interneurons to hippocampal circuit dysfunction caused by amyloid β oligomers.

A bright new look at proteins

Natalie Elia and colleagues present a powerful, easy-to-implement tool for live-cell labeling of proteins with small, genetic code expansion-based fluorescent probes.

A map of RNA editing in the developing brain

Elin Lundin and colleagues use in situ sequencing to reveal the spatiotemporal patterns of RNA editing during mouse brain development, identifying regional, and cell-type specific regulation.

The genomics of oat

Peter Maughan and colleagues report the first chromosome-scale assemblies of the oat species Avena atlantica and Avena eriantha, providing insights into the evolution and complexity of oat.

Long live the king: a chromosome-level assembly of the lion genome

A high-quality, de novo genome assembly for the lion (Panthera leo) by Ellie Armstrong and Dmitri Petrov describes patterns of heterozygosity across cat genomes, and implications of using genomes from captive animals for conservation studies.

Transcriptome and chromatin structure in domesticated animals

Sylvail Foissac, Elisabetta Giuffra and colleagues profile the landscape of transcription, chromatin accessibility and conformation in immune and liver cells of  ruminants, pig and chicken.

Featured Review

Are we there yet? The long walk towards the development of efficient symbiotic associations between nitrogen-fixing bacteria and non-leguminous crops

Vânia C. S. Pankievicz, Thomas B. Irving, Lucas G. S. Maia & Jean-Michel Ané

Published on: 03 December 2019


Genomic adaptations to chemosymbiosis in the deep-sea seep-dwelling tubeworm Lamellibrachia luymesi
Yuanning Li, Michael G. Tassia, Damien S. Waits, Viktoria E. Bogantes, Kyle T. David & Kenneth M. Halanych
Published on: 18 November 2019

Single-cell reconstruction of differentiation trajectory reveals a critical role of ETS1 in human cardiac lineage commitment
Hang Ruan, Yingnan Liao, Zongna Ren, Lin Mao, Fang Yao, Peng Yu, Youqiong Ye, Zhao Zhang, Shengli Li, Hanshi Xu, Jiewei Liu, Lixia Diao, Bingying Zhou, Leng Han & Li Wang
Published on: 13 November 2019

GLIPR1L1 is an IZUMO-binding protein required for optimal fertilization in the mouse
Avinash S. Gaikwad, Amanda L. Anderson, D. Jo Merriner, Anne E. O’Connor, Brendan J. Houston, R. John Aitken, Moira K. O’Bryan & Brett Nixon
Published on: 31 October 2019

Regeneration in the ctenophore Mnemiopsis leidyi occurs in the absence of a blastema, requires cell division, and is temporally separable from wound healing
Julia Ramon-Mateu, S. Tori Ellison, Thomas E. Angelini & Mark Q. Martindale
Published on: 11 October 2019

Concurrent genome and epigenome editing by CRISPR-mediated sequence replacement
Jes Alexander, Gregory M. Findlay, Martin Kircher & Jay Shendure
Published on: 18 November 2019

The microbiome of the upper respiratory tract in health and disease
Christina Kumpitsch, Kaisa Koskinen, Veronika Schöpf & Christine Moissl-Eichinger
Published: 07 November 2019

The human gut bacteria Christensenellaceae are widespread, heritable, and associated with health
Jillian L. Waters & Ruth E. Ley
Published: 28 October 2019

Studying the gut virome in the metagenomic era: challenges and perspectives
Sanzhima Garmaeva, Trishla Sinha, Alexander Kurilshikov, Jingyuan Fu, Cisca Wijmenga & Alexandra Zhernakova
Published: 28 October 2019

Viral hijacking of cellular metabolism
Shivani K. Thaker, James Ch’ng & Heather R. Christofk
Published: 18 July 2019

Multiple levels of the unknown in microbiome research
Andrew Maltez Thomas & Nicola Segata
Published: 12 June 2019

  1. Authors: Winfried Schlee, Nadia Mueller, Thomas Hartmann, Julian Keil, Isabel Lorenz and Nathan Weisz

    Content type: Research article

Focus: The Virome

Read the latest papers on The Virome across BMC flagship journals.

HIV epidemiology among female sex workers and their clients in the Middle East and North Africa: systematic review, meta-analyses, and meta-regressions
Hiam Chemaitelly et al.

Published in BMC Medicine 24 June 2019

Viral diversity is an obligate consideration in CRISPR/Cas9 designs for targeting the HIV reservoir​​​​​​​
Pavitra Roychoudhury et al.

Published in BMC Biology 11 July 2018

Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naïve Parkinson’s disease patients​​​​​​​
J. R. Bedarf et al.

Published in Genome Medicine 28 April 2017

An amplicon-based sequencing framework for accurately measuring intrahost virus diversity using PrimalSeq and iVar​​​​​​​
Nathan D. Grubaugh et al.

Published in Genome Biology 08 January 2019

Find out what is new at BMC Biology

Visit our Goings On page to keep up to date with our news and announcements, article archives and more.

Latest collections

Special issue
Microbiome Biology
BMC Biology


Thematic series
Engineering Biology
BMC Biology

Special issue
Cancer Metabolism
BMC Biology and Cancer & Metabolism

Thematic series
Environment and Sustainability
BMC Biology

Thematic series
Protein Quality Control at Membranes
BMC Biology

Thematic series
New Tools for Neurobiology
BMC Biology

Cross journal collection
In the Light of Evolution

Thematic series
What is Wrong With This Picture?
BMC Biology

View all collections

Latest Tweets