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The Evolution of Regeneration

Ramon-Mateu and colleagues use the comb jelly as a model to show that cell proliferation is required for regeneration in ctenophores, but is separable from wound healing; and might shed light on regenerative diversity among metazoans.

Genetic improvement of Cassava

Wilhelm Gruissem and colleagues compare haplotype-resolved genomes for geminivirus-resistant and geminivirus-susceptible cultivars of African Cassava, illuminating many previously hidden features, and the complex structure of a major disease-resistance locus.

Tracking the gut response to antibiotics

Willmann and colleagues use shotgun metagenomics and multivariate modeling to analyse alterations of the gut microbiome in two patient cohorts receiving distinct prophylactic antibodies.

Engineering Bacterial Microcompartments

In a Q&A from our Engineering Biology series, Henning Kirst and Cheryl Kerfeld explain how bacterial microcompartments, specialized catalysis-enhancing metabolic bacterial organelles, can be modified for metabolic engineering and nanomedicine.

Variable germ plasm composition in Holometabola

A characterization of genes important for germline establishment in the wasp Nasonia vitripennis by Jeremy Lynch and colleagues demonstrates that the mRNA composition of the oosome differs significantly from the Drosophila polar granules.

Structural insights on pesticide targets

Yuchi and colleagues reveal insect-specific structural features in a regulatory domain of the diamondback moth ryanodine receptor, and a potential ligand-binding site for use in developing green pesticides with high species-specificity.

Featured Review

Studying metabolic flux adaptations in cancer through integrated experimental-computational approaches

Shoval Lagziel, Won Dong Lee & Tomer Shlomi

Published on: 04 July 2019

Articles

Methodology
A systematic sequencing-based approach for microbial contaminant detection and functional inference
Sung-Joon Park, Satoru Onizuka, Masahide Seki, Yutaka Suzuki, Takanori Iwata & Kenta Nakai 
Published on: 13 September 2019

Research
Cold-induced lipid dynamics and transcriptional programs in white adipose tissue
Ziye Xu, Wenjing You, Yanbing Zhou, Wentao Chen, Yizhen Wang & Tizhong Shan
Published on: 17 September 2019

Research
Metagenomes and metatranscriptomes shed new light on the microbial-mediated sulfur cycle in a Siberian soda lake
Charlotte D. Vavourakis, Maliheh Mehrshad, Cherel Balkema, Rutger van Hall, Adrian-Ştefan Andrei, Rohit Ghai, Dimitry Y. Sorokin & Gerard Muyzer
Published on: 22 August 2019

Research
Strigolactone synthesis is ancestral in land plants, but canonical strigolactone signalling is a flowering plant innovation
Catriona H. Walker, Karen Siu-Ting, Alysha Taylor, Mary J. O’Connell & Tom Bennett
Published on: 05 September 2019

Research
Distinct impact of antibiotics on the gut microbiome and resistome: a longitudinal multicenter cohort study
Matthias Willmann, Maria J. G. T. Vehreschild, Lena M. Biehl, Wichard Vogel, Daniela Dörfel, Axel Hamprecht, Harald Seifert, Ingo B. Autenrieth & Silke Peter
Published on: 18 September 2019


Review
Synthetic Biology Goes Cell-Free
Aidan Tinafar, Katariina Jaenes & Keith Pardee
Pubished on: 8 August 2019

Review
Viral hijacking of cellular metabolism
Shivani K. Thaker, James Ch’ng & Heather R. Christofk
Published on: 18 July 2019

Comment
Multiple levels of the unknown in microbiome research
Andrew Maltez Thomas & Nicola Segata 
Published on: 12 June 2019

Review
Mitochondrial DNA: the overlooked oncogenome?
Payam A. Gammage & Christian Frezza 
Published on: 08 July 2019

Review
Genetic voltage indicators
Yuki Bando, Christiane Grimm, Victor H Cornejo & Rafael Yuste
Published on: 12 September 2019

  1. Content type: Research article

    Authors: Winfried Schlee, Nadia Mueller, Thomas Hartmann, Julian Keil, Isabel Lorenz and Nathan Weisz

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Focus: Neurology in Health and Disease

Read the latest papers on Neurology across BMC flagship journals.

Clinical and cost-effectiveness of contingency management for cannabis use in early psychosis: the CIRCLE randomised clinical trial​​​​​​
Luke Sheridan Rains, Louise Marston, Mark Hinton, Steven Marwaha, Thomas Craig, David Fowler, Michael King, Rumana Z. Omar, Paul McCrone, Jonathan Spencer, Joanne Taylor, Sophie Colman, Catherine Harder, Eleanor Gilbert, Amie Randhawa, Kirsty Labuschagne, Charlotte Jones, Theodora Stefanidou, Marina Christoforou, Meghan Craig, John Strang, Tim Weaver & Sonia Johnson

Published in BMC Medicine 15 August 2019

Parkinson’s disease-linked Parkin mutations impair glutamatergic signaling in hippocampal neurons
Mei Zhu, Giuseppe P. Cortese & Clarissa L. Waites

Published in BMC Biology 10 September 2018

Red blood cell indices and anaemia as causative factors for cognitive function deficits and for Alzheimer’s disease
Laura M. Winchester, John Powell, Simon Lovestone & Alejo J. Nevado-Holgado

Published in Genome Medicine 28 June 2018

Detection of circular RNA expression and related quantitative trait loci in the human dorsolateral prefrontal cortex​​​​​​​
Zelin Liu, Yuan Ran, Changyu Tao, Sichen Li, Jian Chen & Ence Yang

Published in Genome Biology 20 May 2019

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