BMC Biology

Genomic history of the Italian population

Marco Sazzini, Paolo Garagnani and colleagues retraced Italians' genetic history, showing early divergence and distinct adaptive evolution for people living in the north and south of Italy.

Network deficits in Huntington’s disease neuronal models

Jordi Alberch and colleagues examined the neuronal ensemble activity and network topology of Huntington’s disease model cultures, finding distinct network alterations in striatal and cortical neurons.

Whole-genome duplications and the evolution of hexapods

A comprehensive analysis of hexapod genomes by Dick Roelofs and colleagues finds limited evidence that WGD plays a significant role in the evolution of hexapods.

The genome of a polar dinoflagellate

Genome assemblies of the polar dinoflagellate Polarella glacialis isolated from the Arctic and Antarctica, by Cheong Xin Chan and colleagues shed light on the evolution of dinoflagellates, and the genomic adaptation to extreme cold.

Hybrid origin of Candida albicans

New research from Verónica Mixão and Toni Gabaldón provides genomic evidence that Candida albicans strains derive from a single hybrid ancestor, and diverged by loss of heterozygosity.

Call for papers: Research Synthesis and Meta-research in Biology

We’re inviting submissions to our new Series guest edited by Shinichi Nakagawa, Julia Koricheva, Malcolm Macleod and Wolfgang Viechtbauer.

Articles

A tissue level atlas of the healthy human virome

Authors: Ryuichi Kumata, Jumpei Ito, Kenta Takahashi, Tadaki Suzuki and Kei Sato

Content type: Research article

4 June 2020
Intramembrane proteolysis of an extracellular serine protease, epithin/PRSS14, enables its intracellular nuclear function

Authors: Youngkyung Cho, Sang Bum Kim, Jiyoon Kim, An Vuong Quynh Pham, Min Ji Yoon, Jeong Hwan Park, Ki-Tae Hwang, Dongeun Park, Yongcheol Cho, Moon Gyo Kim and Chungho Kim

Content type: Research article

3 June 2020
Unraveling the molecular interactions involved in phase separation of glucocorticoid receptor

Authors: Martin Stortz, Adali Pecci, Diego M. Presman and Valeria Levi

Content type: Research article

2 June 2020
Deficits in coordinated neuronal activity and network topology are striatal hallmarks in Huntington’s disease

Authors: S. Fernández-García, J. G. Orlandi, G. A. García-Díaz Barriga, M. J. Rodríguez, M. Masana, J. Soriano and J. Alberch

Content type: Research article

28 May 2020
Multi-faceted analysis provides little evidence for recurrent whole-genome duplications during hexapod evolution

Authors: Dick Roelofs, Arthur Zwaenepoel, Tom Sistermans, Joey Nap, Andries A. Kampfraath, Yves Van de Peer, Jacintha Ellers and Ken Kraaijeveld

Content type: Research article

27 May 2020

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Research
Evolutionary superscaffolding and chromosome anchoring to improve Anopheles genome assemblies
Robert M. Waterhouse et al.
Published on: 02 January 2020

Research
Charting the diversity of uncultured viruses of Archaea and Bacteria
F. H. Coutinho et al.
Published on: 29 December 2019

Research
Long live the king: chromosome-level assembly of the lion (Panthera leo) using linked-read, Hi-C, and long-read data
Ellie E. Armstrong et al.
Published on: 08 January 2020

Research
The X chromosome of the German cockroach, Blattella germanica, is homologous to a fly X chromosome despite 400 million years divergence
Richard P. Meisel et al.
Published on: 05 December 2019

Methodology
Spatiotemporal mapping of RNA editing in the developing mouse brain using in situ sequencing reveals regional and cell-type-specific regulation
Elin Lundin et al.
Published on: 14 January 2020

Review
Unlocking the origins and biology of domestic animals using ancient DNA and paleogenomics
Gillian P. McHugo et al.
Published 02 December 2019

Review
Are we there yet? The long walk towards the development of efficient symbiotic associations between nitrogen-fixing bacteria and non-leguminous crops
Vânia C. S. Pankievicz et al.
Published 03 December 2019

Review
The microbiome of the upper respiratory tract in health and disease
Christina Kumpitsch, Kaisa Koskinen, Veronika Schöpf & Christine Moissl-Eichinger
Published: 07 November 2019

Review
The human gut bacteria Christensenellaceae are widespread, heritable, and associated with health
Jillian L. Waters & Ruth E. Ley
Published: 28 October 2019

Review
Studying the gut virome in the metagenomic era: challenges and perspectives
Sanzhima Garmaeva, Trishla Sinha, Alexander Kurilshikov, Jingyuan Fu, Cisca Wijmenga & Alexandra Zhernakova
Published: 28 October 2019

scribblemutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs

Authors: Gregory R Leong, Karen R Goulding, Nancy Amin, Helena E Richardson and Anthony M Brumby

Content type: Research article

24 September 2009
Molecular dynamics simulations and drug discovery

Authors: Jacob D Durrant and J Andrew McCammon

Content type: Review

28 October 2011
Q&A: What is the Golgi apparatus, and why are we asking?

Authors: Sean Munro

Content type: Question and Answer

30 September 2011
Mapping cortical hubs in tinnitus

Authors: Winfried Schlee, Nadia Mueller, Thomas Hartmann, Julian Keil, Isabel Lorenz and Nathan Weisz

Content type: Research article

23 November 2009
Q&A: What are exosomes, exactly?

Authors: James R. Edgar

Content type: Question and Answer

13 June 2016