Adaptive, diverse and de-centralized diagnostics are key to the future of outbreak response
Quinn Matthews et al.
Published 28 October 2020
Domestication of the olive tree
Toni Gabaldón and colleagues shed light into the evolution and domestication of the olive tree, demonstrating a major domestication event, followed by recurrent independent genetic admixture events with wild populations across the Mediterranean Basin.
African swine fever virus gets a past
Martin Beer and colleagues find elements of the African swine fever virus in the genome of soft ticks, providing insights into the evolution of this devastating swine virus and its co-development with its host.
Mutational robustness of protein structures
In a study by Marianne Rooman and Fabrizio Pucci, large-scale in silico experiments estimating the change in folding free energy upon all possible single-site mutations in more than 20,000 protein structures reveal optimization of codon usage for protein mutational robustness.
Genome-enabled insights into the biology of thrips
Dorith Rotenberg and colleagues present the genome of the invasive insect western flower thrips, providing a genetic blueprint for understanding the biology of the pest and to find ways to control it.
Crowdsourcing for new antibiotics
Marek Mutwil and colleagues used crowdsourcing to identify novel components of protein synthesis in bacteria, with 285 undergraduate students processing 26.38 terabytes of RNA-seq data, and predicting more than 100 putative regulators of protein synthesis in 17 bacterial pathogens.
Call for papers: Research Synthesis and Meta-research in Biology
We’re inviting submissions to our new Series guest edited by Shinichi Nakagawa, Julia Koricheva, Malcolm Macleod and Wolfgang Viechtbauer.
Featured Comment
Articles
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Adaptive, diverse and de-centralized diagnostics are key to the future of outbreak response
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Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy
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Hyperactivated Wnt-β-catenin signaling in the absence of sFRP1 and sFRP5 disrupts trophoblast differentiation through repression of Ascl2
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Genomic evidence for recurrent genetic admixture during the domestication of Mediterranean olive trees (Olea europaea L.)
Research
Genomic history of the Italian population recapitulates key evolutionary dynamics of both Continental and Southern Europeans
Marco Sazzini et al.
Published on: 22 May 2020
Research
Wonky whales: the evolution of cranial asymmetry in cetaceans
Ellen Coombs et al.
Published on: 10 July 2020
Research
Tandem gene duplications drive divergent evolution of caffeine and crocin biosynthetic pathways in plants
Zhichao Xu et al.
Published on: 18 June 2020
Research
Relationship between oxygen consumption and neuronal activity in a defined neural circuit
Suzan Özugur et al.
Published on: 03 July 2020
Review
X-ray computed tomography in life sciences
Shelley D. Rawson et al.
Published 27 February 2020
Comment
The merger that made us
Buzz Baum and David Baum
Published 24 June 2020
Review
Protein assembly systems in natural and synthetic biology
Giulio Chiesa et al.
Published: 26 March 2020
Comment
Improving the usability and comprehensiveness of microbial databases
Caitlin Loeffler et al.
Published: 07 April 2020
Focus: Immunology in Health and Disease
Read the latest papers on immunology across BMC flagship journals.
Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection
Daniel M. Muema et al.
Published in BMC Medicine 25 March 2020
The role of T cell trafficking in CTLA-4 blockade-induced gut immunopathology
Shashuang Zhang et al.
Published in BMC Biology 17 March 2020
Multi-omics discovery of exome-derived neoantigens in hepatocellular carcinoma
Markus W. Löffler et al.
Published in Genome Medicine 30 April 2019
Host-associated microbiomes are predicted by immune system complexity and climate
Douglas C. Woodhams et al.
Published in Genome Biology 03 February 2020
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