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Cancer Metabolism Series

Our Series on Cancer Metabolism highlights advances in our understanding of cancer metabolism through commissioned Reviews and Q&As from leaders in the field.

Tackling Waste in Publishing

We consider papers reviewed at other journals on the basis of existing referee reports, and share our reviews with other journals. Find out more about portable peer review at BMC Biology.

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Special issue on Microbiome Biology

A joint special issue by  BMC Biology and Genome Biology explores the pervasive influence of microbial life on ourselves and our living planet.

The Many Unknowns of Microbiome Research

Nicola Segata and colleagues comment on the many kinds of “unknowns” in microbiome research, and whether and how they can be tackled.

The Arsenic Resistome in the Soil Microbiome

Ashley Shade and colleagues perform a comprehensive analysis of the genes contributing to arsenic metabolism and resistance in soil microbiomes, providing a roadmap for the ecological investigation of environmental resistomes.

Building Membranes for Synthetic Cells

In a new Review article Petra Schwille and colleagues discuss membrane transformations during cell division, and strategies for creating artificial cell division machineries.

Featured Comment

Multiple levels of the unknown in microbiome research​​​​​​​

Andrew Maltez Thomas and Nicola Segata

Published on: 12 June 2019


The golden death bacillus Chryseobacterium nematophagum is a novel matrix digesting pathogen of nematodes
Antony P. Page, Mark Roberts, Marie-Anne Félix, Derek Pickard, Andrew Page and William Weir
Published on: 28 February 2019

Inferring cancer dependencies on metabolic genes from large-scale genetic screens
Shoval Lagziel, Won Dong Lee and Tomer Shlomi
Published on: 30 APril 2019

Ontogenetic and phylogenetic simplification during white stripe evolution in clownfishes
Pauline Salis, Natacha Roux, Olivier Soulat, David Lecchini, Vincent Laudet and Bruno Frédérich
Published on: 5 September 2018

In vivo assembly and trafficking of olfactory Ionotropic Receptors
Liliane Abuin, Lucia L. Prieto-Godino, Haiyun Pan, Craig Gutierrez, Lan Huang, Rongsheng Jin and Richard Benton
Published on: 17 April 2019

Derivation of adult canine intestinal organoids for translational research in gastroenterology
Lawrance Chandra, Dana C. Borcherding, Dawn Kingsbury, Todd Atherly, Yoko M. Ambrosini, Agnes Bourgois-Mochel, Wang Yuan, Michael Kimber, Yijun Qi, Qun Wang, Michael Wannemuehler, N. Matthew Ellinwood, Elizabeth Snella, Martin Martin, Melissa Skala, David Meyerholz, Mary Estes, Martin E. Fernandez-Zapico, Albert E. Jergens, Jonathan P. Mochel and Karin Allenspach
Published on: 11 April 2019

Cell size sensing—a one-dimensional solution for a three-dimensional problem?
Ida Rishal and Mike Fainzilber
Pubished on: 29 April 2019

Open questions: CRISPR biology
Eugene V. Koonin
Published on: 24 September 2018

Open questions: How many genes do we have?
Steven L. Salzberg
Published on: 20 August 2018

Open questions: why are babies rarely born with cancer?
Michelle Monje
Published on: 1 November 2018

Horizons in the evolution of aging
Thomas Flatt and Linda Partridge
Published on: 20 August 2018

  1. Content type: Research article


    Authors: Winfried Schlee, Nadia Mueller, Thomas Hartmann, Julian Keil, Isabel Lorenz and Nathan Weisz

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Focus: Immunology in Health and Disease

Read the latest papers on immunology across BMC flagship journals.

A step beyond the hygiene hypothesis—immune-mediated classes determined in a population-based study
Vladeta Ajdacic-Gross, Margot Mutsch, Stephanie Rodgers, Anja Tesic, Mario Müller, Erich Seifritz, En-Young N. Wagner, Roland von Känel, Markus A. Landolt, Nina Steinemann, Viktor von Wyl, Enrique Castelao, Marie-Pierre F. Strippoli, Jennifer Glaus, Caroline Vandeleur, Pedro M. Marques-Vidal, Peter Vollenweider and Martin Preisig
Published in BMC Medicine on: 9 April 2019

Time-resolved transcriptome and proteome landscape of human regulatory T cell (Treg) differentiation reveals novel regulators of FOXP3
Angelika Schmidt, Francesco Marabita, Narsis A. Kiani, Catharina C. Gross, Henrik J. Johansson, Szabolcs Éliás, Sini Rautio, Matilda Eriksson, Sunjay Jude Fernandes, Gilad Silberberg, Ubaid Ullah, Urvashi Bhatia, Harri Lähdesmäki, Janne Lehtiö, David Gomez-Cabrero, Heinz Wiendl, Riitta Lahesmaa and Jesper Tegnér
Published in BMC Biology on: 7 May 2018

Single-cell transcriptomics reveal that PD-1 mediates immune tolerance by regulating proliferation of regulatory T cells
Cherry S. Leung, Kevin Y. Yang, Xisheng Li, Vicken W. Chan, Manching Ku, Herman Waldmann, Shohei Hori, Jason C. H. Tsang, Yuk Ming Dennis Lo and Kathy O. Lui
Published in Genome Medicine on: 20 September 2018

Exploring the genetic basis of human population differences in DNA methylation and their causal impact on immune gene regulation
Lucas T. Husquin, Maxime Rotival, Maud Fagny, Hélène Quach, Nora Zidane, Lisa M. McEwen, Julia L. MacIsaac, Michael S. Kobor, Hugues Aschard, Etienne Patin and Lluis Quintana-Murci
Published in Genome Biology on: 18 December 2018

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