Eugene V. Koonin, Mart Krupovic, Sonoko Ishino and Yoshizumi Ishino.
Published 09 June 2020
The genome sequence of Gardenia jasminoides yields insights into the ways gene duplications drove the divergent evolution of the crocin and caffeine biosynthetic pathways.
Using multi-omics approaches, Dominique Soldati-Favre and colleagues examine the role of distinct acetyl-CoA subcellular pools in the pathogen Toxoplasma gondii, identifying their distinct roles in the synthesis of parasite-specific fatty acids, and impact on metabolic processes.
Mapping bacterial genomes and metabolic capacities allowed the identification of the evolutionary processes driving metabolic diversity in the Candidate Phyla Radiation lineages.
DNA methylation analysis based on pyrosequencing, ddPCR, and BBA-seq approaches enables high-precision epigenetic age-predictions and demonstrated that the stochastic evolution of age-associated methylation patterns enables epigenetic clocks for individual DNA strands.
We’re inviting submissions to our new Series guest edited by Shinichi Nakagawa, Julia Koricheva, Malcolm Macleod and Wolfgang Viechtbauer.
Evolutionary superscaffolding and chromosome anchoring to improve Anopheles genome assemblies
Robert M. Waterhouse et al.
Published on: 02 January 2020
Charting the diversity of uncultured viruses of Archaea and Bacteria
F. H. Coutinho et al.
Published on: 29 December 2019
Long live the king: chromosome-level assembly of the lion (Panthera leo) using linked-read, Hi-C, and long-read data
Ellie E. Armstrong et al.
Published on: 08 January 2020
The X chromosome of the German cockroach, Blattella germanica, is homologous to a fly X chromosome despite 400 million years divergence
Richard P. Meisel et al.
Published on: 05 December 2019
Spatiotemporal mapping of RNA editing in the developing mouse brain using in situ sequencing reveals regional and cell-type-specific regulation
Elin Lundin et al.
Published on: 14 January 2020
Unlocking the origins and biology of domestic animals using ancient DNA and paleogenomics
Gillian P. McHugo et al.
Published 02 December 2019
Are we there yet? The long walk towards the development of efficient symbiotic associations between nitrogen-fixing bacteria and non-leguminous crops
Vânia C. S. Pankievicz et al.
Published 03 December 2019
The microbiome of the upper respiratory tract in health and disease
Christina Kumpitsch, Kaisa Koskinen, Veronika Schöpf & Christine Moissl-Eichinger
Published: 07 November 2019
The human gut bacteria Christensenellaceae are widespread, heritable, and associated with health
Jillian L. Waters & Ruth E. Ley
Published: 28 October 2019
Studying the gut virome in the metagenomic era: challenges and perspectives
Sanzhima Garmaeva, Trishla Sinha, Alexander Kurilshikov, Jingyuan Fu, Cisca Wijmenga & Alexandra Zhernakova
Published: 28 October 2019
Read the latest papers on cancer across BMC flagship journals.
Lifestyle factors and risk of multimorbidity of cancer and cardiometabolic diseases: a multinational cohort study
Heinz Freisling et al.
Published in BMC Medicine 10 January 2020
Joint learning improves protein abundance prediction in cancers
Hongyang Li et al.
Published in BMC Biology 23 December 2019
Comprehensive characterization of circular RNAs in ~ 1000 human cancer cell lines
Hang Ruan et al.
Published in Genome Medicine 26 August 2019
Integrative analyses of the RNA modification machinery reveal tissue- and cancer-specific signatures
Oguzhan Begik et al.
Published in Genome Biology 07 May 2020
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Announcement: COVID-19 and impact on peer review
As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times. Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.