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Methodology article
Recent developments in droplet-based microfluidics allow the transcriptional profiling of thousands of individual cells in a quantitative, highly parallel and cost-effective way. A critical, often limiting ste...
BMC Biology 2017 15:44
Published on: 19 May 2017
Methodology article
Intravascular leukocyte recruitment in most vertebrate tissues is restricted to postcapillary and collecting venules, whereas capillaries and arterioles usually support little or no leukocyte adhesion. This se...
BMC Biology 2017 15:45
Published on: 19 May 2017
Comment
Senses connect organisms to both the world and to each other, yet there is much we don’t know about them. Using examples drawn primarily from the author’s subfield of vision research, this article discusses fi...
BMC Biology 2017 15:43
Published on: 17 May 2017
Commentary
Improvements in imaging technology and the development of powerful machine learning algorithms are revolutionizing the study of animal behavior in the laboratory. These innovations promise to reveal both globa...
BMC Biology 2017 15:42
Published on: 15 May 2017
Software
Accurate determination of mouse positions from video data is crucial for various types of behavioral analyses. While detection of body positions is straightforward, the correct identification of nose positions...
BMC Biology 2017 15:41
Published on: 15 May 2017
Research article
Endogenous circadian oscillators distributed across the mammalian body are synchronised among themselves and with external time via a variety of signalling molecules, some of which interact with G-protein-coup...
BMC Biology 2017 15:40
Published on: 15 May 2017
Research article
Plant-pathogenic oomycetes are responsible for economically important losses in crops worldwide. Phytophthora palmivora, a tropical relative of the potato late blight pathogen, causes rotting diseases in many tro...
BMC Biology 2017 15:39
Published on: 11 May 2017
Research article
The merging of genomes in inter-specific hybrids can result in novel phenotypes, including increased growth rate and biomass yield, a phenomenon known as heterosis. Heterosis is typically viewed as the opposit...
BMC Biology 2017 15:38
Published on: 11 May 2017
Comment
Biological systems integrate multiscale processes and networks and are, therefore, viewed as difficult to dissect. However, because of the clear-cut separation between the software code (the information encode...
BMC Biology 2017 15:37
Published on: 8 May 2017
Review
Emerging pathogens of crops threaten food security and are increasingly problematic due to intensive agriculture and high volumes of trade and transport in plants and plant products. The ability to predict pat...
BMC Biology 2017 15:36
Published on: 8 May 2017
Research article
Animal olfactory systems detect volatile environmental chemicals and integrate this information to direct the discovery of food and mates as well as danger avoidance. Rather than remaining constant, olfactory ...
BMC Biology 2017 15:35
Published on: 5 May 2017
Review
The misfolding of the cellular prion protein (PrPC) causes fatal neurodegenerative diseases. Yet PrPC is highly conserved in mammals, suggesting that it exerts beneficial functions preventing its evolutionary eli...
BMC Biology 2017 15:34
Published on: 2 May 2017
Research article
Stereotypic cleavage patterns play a crucial role in cell fate determination by precisely positioning early embryonic blastomeres. Although misplaced cell divisions can alter blastomere fates and cause embryon...
BMC Biology 2017 15:33
Published on: 28 April 2017
Research article
Fishes are extremely speciose and also highly disparate in their fin configurations, more specifically in the number of fins present as well as their structure, shape, and size. How they achieved this remarkab...
BMC Biology 2017 15:32
Published on: 27 April 2017
Research article
Trimeric intracellular cation (TRIC) channels are crucial for Ca2+ handling in eukaryotes and are involved in K+ uptake in prokaryotes. Recent studies on the representative members of eukaryotic and prokaryotic T...
BMC Biology 2017 15:31
Published on: 22 April 2017
Research article
Exercise exerts remarkably powerful effects on metabolism and health, with anti-disease and anti-aging outcomes. Pharmacological manipulation of exercise benefit circuits might improve the health of the sedent...
BMC Biology 2017 15:30
Published on: 10 April 2017
Research article
Most agronomic traits in rice are complex and polygenic. The identification of quantitative trait loci (QTL) for grain length is an important objective of rice genetic research and breeding programs.
BMC Biology 2017 15:28
Published on: 6 April 2017
Methodology article
Animals exhibit astonishingly complex behaviors. Studying the subtle features of these behaviors requires quantitative, high-throughput, and accurate systems that can cope with the often rich perplexing data.
BMC Biology 2017 15:29
Published on: 6 April 2017
Comment
All of us have marveled at the remarkable diversity of animal behaviors in nature.
BMC Biology 2017 15:26
Published on: 3 April 2017
Research article
Mitochondria of opisthokonts undergo permanent fission and fusion throughout the cell cycle. Here, we investigated the dynamics of the mitosomes, the simplest forms of mitochondria, in the anaerobic protist pa...
BMC Biology 2017 15:27
Published on: 3 April 2017
Methodology article
Contamination is a well-known but often neglected problem in molecular biology. Here, we investigated the prevalence of cross-contamination among 446 samples from 116 distinct species of animals, which were pr...
BMC Biology 2017 15:25
Published on: 29 March 2017
Research article
The fate of hydrogen peroxide (H2O2) in the endoplasmic reticulum (ER) has been inferred indirectly from the activity of ER-localized thiol oxidases and peroxiredoxins, in vitro, and the consequences of their gen...
BMC Biology 2017 15:24
Published on: 27 March 2017
Question and Answer
Salicylic acid (SA) is an important plant hormone that regulates many aspects of plant growth and development, as well as resistance to (a)biotic stress. Efforts to identify SA effector proteins have revealed ...
BMC Biology 2017 15:23
Published on: 23 March 2017
Research article
Defining the transcriptome and the genetic pathways of pancreatic cells is of great interest for elucidating the molecular attributes of pancreas disorders such as diabetes and cancer. As the function of the d...
BMC Biology 2017 15:21
Published on: 21 March 2017
Methodology article
In addition to messenger RNA (mRNA), noncoding RNAs (ncRNAs) are essential components in cellular machineries for translation and splicing. Besides their housekeeping functions, ncRNAs are involved in cell typ...
BMC Biology 2017 15:22
Published on: 21 March 2017
