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  1. Erratum

    Erratum to: Genomic innovations, transcriptional plasticity and gene loss underlying the evolution and divergence of two highly polyphagous and invasive Helicoverpa pest species

    S. L. Pearce, D. F. Clarke, P. D. East, S. Elfekih, K. H. J. Gordon, L. S. Jermiin, A. McGaughran, J. G. Oakeshott, A. Papanicolaou, O. P. Perera, R. V. Rane, S. Richards, W. T. Tay, T. K. Walsh, A. Anderson, C. J. Anderson…

    BMC Biology 2017 15:69

    Published on: 15 August 2017

    The original article was published in BMC Biology 2017 15:63

  2. Research article

    Genomic innovations, transcriptional plasticity and gene loss underlying the evolution and divergence of two highly polyphagous and invasive Helicoverpa pest species

    Helicoverpa armigera and Helicoverpa zea are major caterpillar pests of Old and New World agriculture, respectively. Both, particularly H. armigera, are extremely polyphagous, and H. a...

    S. L. Pearce, D. F. Clarke, P. D. East, S. Elfekih, K. H. J. Gordon, L. S. Jermiin, A. McGaughran, J. G. Oakeshott, A. Papanikolaou, O. P. Perera, R. V. Rane, S. Richards, W. T. Tay, T. K. Walsh, A. Anderson, C. J. Anderson…

    BMC Biology 2017 15:63

    Published on: 31 July 2017

    The Erratum to this article has been published in BMC Biology 2017 15:69

  3. Research article

    The house spider genome reveals an ancient whole-genome duplication during arachnid evolution

    The duplication of genes can occur through various mechanisms and is thought to make a major contribution to the evolutionary diversification of organisms. There is increasing evidence for a large-scale duplic...

    Evelyn E. Schwager, Prashant P. Sharma, Thomas Clarke, Daniel J. Leite, Torsten Wierschin, Matthias Pechmann, Yasuko Akiyama-Oda, Lauren Esposito, Jesper Bechsgaard, Trine Bilde, Alexandra D. Buffry, Hsu Chao, Huyen Dinh, HarshaVardhan Doddapaneni, Shannon Dugan, Cornelius Eibner…

    BMC Biology 2017 15:62

    Published on: 31 July 2017

  4. Research article

    Silicanin-1 is a conserved diatom membrane protein involved in silica biomineralization

    Biological mineral formation (biomineralization) proceeds in specialized compartments often bounded by a lipid bilayer membrane. Currently, the role of membranes in biomineralization is hardly understood.

    Alexander Kotzsch, Philip Gröger, Damian Pawolski, Paul H. H. Bomans, Nico A. J. M. Sommerdijk, Michael Schlierf and Nils Kröger

    BMC Biology 2017 15:65

    Published on: 24 July 2017

  5. Research article

    Charged residues next to transmembrane regions revisited: “Positive-inside rule” is complemented by the “negative inside depletion/outside enrichment rule”

    Transmembrane helices (TMHs) frequently occur amongst protein architectures as means for proteins to attach to or embed into biological membranes. Physical constraints such as the membrane’s hydrophobicity and...

    James Alexander Baker, Wing-Cheong Wong, Birgit Eisenhaber, Jim Warwicker and Frank Eisenhaber

    BMC Biology 2017 15:66

    Published on: 24 July 2017

    The Erratum to this article has been published in BMC Biology 2017 15:72

  6. Research article

    C. elegans SUP-46, an HNRNPM family RNA-binding protein that prevents paternally-mediated epigenetic sterility

    In addition to DNA, gametes contribute epigenetic information in the form of histones and non-coding RNA. Epigenetic programs often respond to stressful environmental conditions and provide a heritable history...

    Wendy L. Johnston, Aldis Krizus, Arun K. Ramani, Wade Dunham, Ji Young Youn, Andrew G. Fraser, Anne-Claude Gingras and James W. Dennis

    BMC Biology 2017 15:61

    Published on: 17 July 2017

  7. Review

    Life behind the wall: sensing mechanical cues in plants

    There is increasing evidence that all cells sense mechanical forces in order to perform their functions. In animals, mechanotransduction has been studied during the establishment of cell polarity, fate, and di...

    Olivier Hamant and Elizabeth S. Haswell

    BMC Biology 2017 15:59

    Published on: 11 July 2017

  8. Question and Answer

    Q&A: using Patch-seq to profile single cells

    Individual neurons vary widely in terms of their gene expression, morphology, and electrophysiological properties. While many techniques exist to study single-cell variability along one or two of these dimensi...

    Cathryn R. Cadwell, Rickard Sandberg, Xiaolong Jiang and Andreas S. Tolias

    BMC Biology 2017 15:58

    Published on: 6 July 2017

  9. Research article

    Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species

    The aggregation of the protein ɑ-synuclein (ɑS) underlies a range of increasingly common neurodegenerative disorders including Parkinson’s disease. One widely explored therapeutic strategy for these conditions...

    Marija Iljina, Liu Hong, Mathew H. Horrocks, Marthe H. Ludtmann, Minee L. Choi, Craig D. Hughes, Francesco S. Ruggeri, Tim Guilliams, Alexander K. Buell, Ji-Eun Lee, Sonia Gandhi, Steven F. Lee, Clare E. Bryant, Michele Vendruscolo, Tuomas P. J. Knowles, Christopher M. Dobson…

    BMC Biology 2017 15:57

    Published on: 3 July 2017

  10. Research article

    Evolution of strigolactone receptors by gradual neo-functionalization of KAI2 paralogues

    Strigolactones (SLs) are a class of plant hormones that control many aspects of plant growth. The SL signalling mechanism is homologous to that of karrikins (KARs), smoke-derived compounds that stimulate seed ...

    Rohan Bythell-Douglas, Carl J. Rothfels, Dennis W. D. Stevenson, Sean W. Graham, Gane Ka-Shu Wong, David C. Nelson and Tom Bennett

    BMC Biology 2017 15:52

    Published on: 29 June 2017

  11. Review

    Tissue macrophages: heterogeneity and functions

    Macrophages are present in all vertebrate tissues, from mid-gestation throughout life, constituting a widely dispersed organ system. They promote homeostasis by responding to internal and external changes with...

    Siamon Gordon and Annette Plüddemann

    BMC Biology 2017 15:53

    Published on: 29 June 2017

  12. Research article

    Mov10 suppresses retroelements and regulates neuronal development and function in the developing brain

    Moloney leukemia virus 10 (Mov10) is an RNA helicase that mediates access of the RNA-induced silencing complex to messenger RNAs (mRNAs). Until now, its role as an RNA helicase and as a regulator of retrotrans...

    Geena Skariah, Joseph Seimetz, Miles Norsworthy, Monica C. Lannom, Phillip J. Kenny, Mohamed Elrakhawy, Craig Forsthoefel, Jenny Drnevich, Auinash Kalsotra and Stephanie Ceman

    BMC Biology 2017 15:54

    Published on: 29 June 2017

  13. Forum

    Non-model model organisms

    Model organisms are widely used in research as accessible and convenient systems to study a particular area or question in biology. Traditionally only a handful of organisms have been widely studied, but moder...

    James J. Russell, Julie A. Theriot, Pranidhi Sood, Wallace F. Marshall, Laura F. Landweber, Lillian Fritz-Laylin, Jessica K. Polka, Snezhana Oliferenko, Therese Gerbich, Amy Gladfelter, James Umen, Magdalena Bezanilla, Madeline A. Lancaster, Shuonan He, Matthew C. Gibson, Bob Goldstein…

    BMC Biology 2017 15:55

    Published on: 29 June 2017

  14. Comment

    Organelle acidification: an ancient cellular leak detector

    Intracellular membrane-bounded organelles of eukaryotic cells transiently contact the extracellular environment during endocytosis and secretion. Such contacts must be precisely timed to prevent leakage of car...

    Mukund Thattai

    BMC Biology 2017 15:51

    Published on: 26 June 2017

  15. Question and Answer

    Q&A: Expansion microscopy

    Expansion microscopy (ExM) is a recently invented technology that uses swellable charged polymers, synthesized densely and with appropriate topology throughout a preserved biological specimen, to physically ma...

    Ruixuan Gao, Shoh M. Asano and Edward S. Boyden

    BMC Biology 2017 15:50

    Published on: 19 June 2017

  16. Editorial

    Who needs registered reports?

    Registered Reports, an article format initiated to help promote transparency and reproducibility in the preclinical and social sciences, are spreading into the biological literature. The format is now offered by

    Miranda Robertson

    BMC Biology 2017 15:49

    Published on: 15 June 2017

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