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Table 4 Tests of Neutrality in PGL genes

From: Sequence variation in human succinate dehydrogenase genes: evidence for long-term balancing selection on SDHA

Locus Length (bp)* Population Sample size
(n)†
S‡ % θs % π Tajima
D test statistic
Fu and Li
D* test statistic
Fu and Li
F* test statistic
SDHB 1710 AA 24 3 0.04 0.016 -1.24 (0.117) -1.70 (0.152) -1.82 (0.080)
  1710 EA 24 0 0 0 -- -- --
  1710 All 48 3 0.034 0.008 -1.37 (0.071) -1.98 (0.113) -2.10 (0.044)
SDHC 1806 AA 24 7 0.087 0.064 -0.724 (0.266) 0.472 (0.186) 0.107 (0.463)
  1806 EA 24 1 0.012 0.005 -0.87 (0.362) 0.55 (0.237) 0.16 (0.238)
  1806 All 48 7 0.075 0.039 -1.150 (0.126) 0.328 (0.233) -0.201 (0.411)
SDHD 2033 AA 24 5 0.055 0.076 0.887 (0.166) 0.144 (0.282) 0.438 (0.329)
  2033 EA 24 0 0 0 -- -- --
  2033 All 48 5 0.048 0.044 -0.195 (0.490) -0.017 (0.334) -0.089 (0.461)
  1. AA, African American samples; EA, European American samples; SD, standard deviation.
  2. Significant p values (within parentheses) are in bold.
  3. *Includes coding and non-coding sequences.
  4. †Number of unrelated subjects.
  5. ‡Number of segregating sites. DnaSp software excludes from the analyses the insertion/deletion variants, one of which is in SDHC.