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Table 4 Tests of Neutrality in PGL genes

From: Sequence variation in human succinate dehydrogenase genes: evidence for long-term balancing selection on SDHA

Locus

Length (bp)*

Population

Sample size

(n)†

S‡

% θs

% π

Tajima

D test statistic

Fu and Li

D* test statistic

Fu and Li

F* test statistic

SDHB

1710

AA

24

3

0.04

0.016

-1.24 (0.117)

-1.70 (0.152)

-1.82 (0.080)

 

1710

EA

24

0

0

0

--

--

--

 

1710

All

48

3

0.034

0.008

-1.37 (0.071)

-1.98 (0.113)

-2.10 (0.044)

SDHC

1806

AA

24

7

0.087

0.064

-0.724 (0.266)

0.472 (0.186)

0.107 (0.463)

 

1806

EA

24

1

0.012

0.005

-0.87 (0.362)

0.55 (0.237)

0.16 (0.238)

 

1806

All

48

7

0.075

0.039

-1.150 (0.126)

0.328 (0.233)

-0.201 (0.411)

SDHD

2033

AA

24

5

0.055

0.076

0.887 (0.166)

0.144 (0.282)

0.438 (0.329)

 

2033

EA

24

0

0

0

--

--

--

 

2033

All

48

5

0.048

0.044

-0.195 (0.490)

-0.017 (0.334)

-0.089 (0.461)

  1. AA, African American samples; EA, European American samples; SD, standard deviation.
  2. Significant p values (within parentheses) are in bold.
  3. *Includes coding and non-coding sequences.
  4. †Number of unrelated subjects.
  5. ‡Number of segregating sites. DnaSp software excludes from the analyses the insertion/deletion variants, one of which is in SDHC.