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Table 1 Phenotypes of Pygo2 wild-type, heterozyogous, and null E18.5 embryos on a Pygo1 null background.

From: Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development

  Pygo2 +/+ Pygo2 +/- Pygo2 -/-
Sample size 6 14 10
Observed phenotypes    
   Average weight (g) 1.36 1.33 0.97 *
   Cleft palate 0 0 6
   Exencephaly 0 0 2
   Lens defect 0 0 10
   Reabsorption/in utero death 0 0 2
  1. * Denotes a significant change (p < 0.01) of the average weight of the Pygo2 null group compared with both the Pygo wild-type and heterozygous groups.
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BMC Biology

ISSN: 1741-7007

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