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Table 1 Phenotypes of Pygo2 wild-type, heterozyogous, and null E18.5 embryos on a Pygo1 null background.

From: Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development

 

Pygo2 +/+

Pygo2 +/-

Pygo2 -/-

Sample size

6

14

10

Observed phenotypes

   

   Average weight (g)

1.36

1.33

0.97 *

   Cleft palate

0

0

6

   Exencephaly

0

0

2

   Lens defect

0

0

10

   Reabsorption/in utero death

0

0

2

  1. * Denotes a significant change (p < 0.01) of the average weight of the Pygo2 null group compared with both the Pygo wild-type and heterozygous groups.