Skip to main content

Advertisement

Table 1 Genetic variation in Neisseria MLST alleles

From: Species status of Neisseria gonorrhoeae: evolutionary and epidemiological inferences from multilocus sequence typing

   149 N. gonorrhoeae isolates 217 N. meningitidis isolates 103 N. lactamica isolates
Locus Size (bp) No. of alleles (no./100 isolates) No. (%) of polymorphic sites d N d S * No. of alleles (no./100 isolates) No. (%) of polymorphic sites d N /d S No. of alleles (no./100 isolates) No. (%) of polymorphic sites d N /d S
abcZ 432 7 (5.1) 6 (1.4) 0.177 21 (9.6) 75 (17.4) 0.074 12 (11.7) 45 (10.4) 0.154
adk 465 3 (2.2) 3 (0.6) 0.583 19 (8.7) 25 (5.4) 0.011 18 (17.5) 43 (9.3) 0.014
aroE 489 2 (1.5) 1 (0.2) 0† 21 (9.6) 135 (27.6) 0.295 16 (15.5) 45 (9.2) 0.464
fumC 465 9 (6.6) 7 (1.5) 0.069 29 (13.3) 48 (10.3) 0.010 19 (18.5) 44 (9.5) 0.042
gdh 501 10 (6.7) 6 (1.2) 0.147 19 (8.7) 26 (5.2) 0.049 26 (25.2) 46 (9.2) 0.047
pdhC 480 3 (2.2) 2 (0.4) 0.328 25 (11.5) 83 (17.3) 0.068 11 (17.5) 15 (3.1) 0.024
pgm 450 3 (2.2) 2 (0.4) 0.298 25 (11.5) 81 (18.0) 0.113 22 (21.4) 96 (21.3) 0.095
  1. *d N /d S the proportion of nonsynonymous to synonymous nucleotide substitutions
  2. † No nonsynonymous changes present at this locus