Table 1 Genetic variation in Neisseria MLST alleles
| Â | Â | 149 N. gonorrhoeae isolates | 217 N. meningitidis isolates | 103 N. lactamica isolates | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
Locus | Size (bp) | No. of alleles (no./100 isolates) | No. (%) of polymorphic sites | d N d S * | No. of alleles (no./100 isolates) | No. (%) of polymorphic sites | d N /d S | No. of alleles (no./100 isolates) | No. (%) of polymorphic sites | d N /d S |
abcZ | 432 | 7 (5.1) | 6 (1.4) | 0.177 | 21 (9.6) | 75 (17.4) | 0.074 | 12 (11.7) | 45 (10.4) | 0.154 |
adk | 465 | 3 (2.2) | 3 (0.6) | 0.583 | 19 (8.7) | 25 (5.4) | 0.011 | 18 (17.5) | 43 (9.3) | 0.014 |
aroE | 489 | 2 (1.5) | 1 (0.2) | 0†| 21 (9.6) | 135 (27.6) | 0.295 | 16 (15.5) | 45 (9.2) | 0.464 |
fumC | 465 | 9 (6.6) | 7 (1.5) | 0.069 | 29 (13.3) | 48 (10.3) | 0.010 | 19 (18.5) | 44 (9.5) | 0.042 |
gdh | 501 | 10 (6.7) | 6 (1.2) | 0.147 | 19 (8.7) | 26 (5.2) | 0.049 | 26 (25.2) | 46 (9.2) | 0.047 |
pdhC | 480 | 3 (2.2) | 2 (0.4) | 0.328 | 25 (11.5) | 83 (17.3) | 0.068 | 11 (17.5) | 15 (3.1) | 0.024 |
pgm | 450 | 3 (2.2) | 2 (0.4) | 0.298 | 25 (11.5) | 81 (18.0) | 0.113 | 22 (21.4) | 96 (21.3) | 0.095 |